When centipedegrass was unmowed, seedhead suppression generally was better with imazethapyr than with mefluidide either alone or with flurprimidol, but these treatments were not effective for 8 weeks. In several instances, imazethapyr at 0.30 kg ai/ha and MH at 2.2 and 4.5 kg ai/ha severely injured (>30%) centipedegrass. Mowing weekly did not control seedhead development effectively, and none of the plant growth regulator plus mowing treatments effectively suppressed seedheads for 12 weeks. To effectively suppress seedhead production for 8 weeks, centipedegrass treated with mefluidide required mowing 3 weeks after treatment, while centipedegrass treated with imazethapyr or flurprimidol plus mefluidide required mowing at 3 and 6 weeks.