This article explores the question of human agency in military targeting. Targeting is one of the key drivers of war. When studied by academic disciplines, much interest has been devoted to the ethics and effects of military targeting. Less debated, but focused here, is the question of the conditions of human agency within military targeting. In the literature that does exist on this topic, there is a questioning of the traditional conception of human agency but at the same time a lack of closer conceptualisation of different kinds of articulations of human agency in the targeting process. In this article, we propose a recentring of human agency in critical scholarship on military targeting. With inspiration from Theodore Schatzki's work on ‘practice’, by analytically approaching targeting as a practice, and through various examples from Operation Iraqi Freedom, the article develops and illustrates a framework for the conceptualisation of human agencies in targeting. This framework distinguishes articulations of agency based on whether they furthered the (temporary) ordering of the targeting practice or challenged its internal organising elements. The study of military targeting is significant not least since the phenomenon is one of the key ‘engines’ and drivers of war's constant becoming.