In greenhouse studies, the American strain of Striga gesnerioides (Willd.) Vatke, indigo witchweed, was potted with a wide range of potential hosts, including some known to be parasitized by this species elsewhere, and with agricultural and ornamental crops of importance in the southern United States. The host range of the indigo witchweed was very limited and no major crop species were seriously affected. Based on these host studies, it appears that indigo witchweed poses little danger to American agriculture. Other strains of the parasite were likewise shown to be host specific.