This paper examines some neglected aspects of Hippocratic medicine, drawing special attention to certain methodological questions concerning the role of sense perception in the acquisition of medical knowledge. I argue that there is greater epistemological uniformity among the texts of the Hippocratic Corpus than is sometimes assumed. I provide a careful reading of seemingly inconsistent Hippocratic treatises in the light of a plausible and coherent epistemological model. The impression that we are dealing with different, indeed inconsistent, epistemological views can be explained away by the specific dialectical contexts of each work and their historical background. Most importantly, a proper justification of this model will require us to delve into the epistemological foundations of Hippocratic medicine.