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1 results

  • 18FDG-PET metabolic response of non-small-cell lung cancer to chemoradiotherapy with long-term follow-up

  • Federico Ampil, Gloria Caldito, Troy Richards
  • Journal:
    Journal of Radiotherapy in Practice / Volume 17 / Issue 1 / March 2018
    Published online by Cambridge University Press:
    11 October 2017, pp. 131-134
  • Aim

    18Fluorodeoxyglucose-positron emission tomography (FDG-PET) can indicate the presence or absence of non-small-cell lung cancer (NSCLC) after treatment. We present a description of the FDG-PET results following the contemporary management of locally advanced NSCLC including long-term outcomes.

    Methodology

    The study participants were eight long-term survivors with metabolic tumour response (MTR) shown on FDG-PET following chemoradiotherapy for locally advanced stage NSCLC between June 2005 and April 2009.

    Results

    After therapy, MTR was complete in five patients; four subjects were free of cancer, and one patient experienced progression of disease at the time of last follow-up. Of the three individuals with incomplete MTRs, distant metastases developed in two patients, and one subject remained disease-free. Long-term survival ranged from 37 to 75 months.

    Conclusion

    Although the number of cases is small, our observations confirm the diagnostic role of FDG-PET as well as its value for predicting prognosis in the clinical practice of oncology.