A new Spiogalea species is described from South-east Brazil. The specimens were collected in muddy bottoms during a large survey (15–3000 m) in southern Brazil. This genus comprised, up to now, only one species described from Capbreton Canyon (Bay of Biscay). The new species differs from the type-species, mostly in the morphology of the prostomial chitinous plate, a character restricted to the genus Spiogalea. With this new species, the generic diagnosis of the genus was amended.