The present study examines differences in functional cerebral
asymmetries modulated by gonadal steroid hormones during the menstrual
cycle in women. Twenty-one right-handed women with regular menstrual
cycles performed a double-stream rapid serial visual presentation (RSVP)
task, with one stream in each visual field, during the low steroid menses
and the high steroid midluteal phase. They were required to detect a
target item, and then a probe item, each of which could appear in either
stream. If the probe item appeared 200 ms after the target, detection of
the probe was impaired—a phenomenon known as the “attentional
blink.” This occurred in both streams in the midluteal phase, but
only in the right visual field during menses. Thus low steroid levels
appeared to restrict the attentional blink to the left hemisphere, while
high levels of estradiol and progesterone in the midluteal phase appeared
to reduce functional asymmetries by selectively increasing the attentional
blink in the right hemisphere. This effect appears to be mediated by
estradiol rather than progesterone, and it is compatible with the
assumption of a hormone-related suppression of right hemisphere functions
during the midluteal phase. (JINS, 2005, 11,
263–272.)