In 12 trials in Louisiana, sicklepod, entireleaf morningglory, pitted morningglory, and hemp sesbania control 4 wk after planting was greater with trifluralin applied PPI followed by chlorimuron plus metribuzin applied PRE than with trifluralin plus flumetsulam applied PPI. Sicklepod control with these herbicides was similar 6 wk after application. No differences in soybean yield were noted. Chlorimuron applied POST following trifluralin applied PPI and metribuzin applied PRE or trifluralin plus flumetsulam applied PPI improved weed control and soybean yield compared with soil-applied herbicides alone. Excellent barnyardgrass control was obtained with all herbicide programs.