This article details how and why officials in the United States and the Federation of Rhodesia and Nyasaland developed policies and initiatives to promote US capital investments. It analyzes these policies in the context of decolonization, white minority rule, and the Cold War in Africa. It further shows how US business interests, especially in the mining industry, increased their investments and influenced policy. Drawing from Zimbabwean archives, it argues that these competing priorities produced inconsistent results that tended to support US imperialism and hinder nationalist movements in British Central Africa.