Greenhouse and field studies were conducted in 1991 and 1992 to determine the potential for interaction among pyridate (0.5, 1.0 kg ai/ha), sethoxydim (0.22 kg ai/ha), and crop oil concentrate (COC) (1.25% v/v) applied alone or in two- and three-way combinations to transplanted cabbage. Additionally, the effect of applying sethoxydim and COC 1 and 2 d before and after application of pyridate was investigated. In greenhouse-grown cabbage, injury increased twofold and dry weight was reduced 15% when pyridate dose was doubled. Sethoxydim increased pyridate injury significantly, reducing dry weight 31%. When COC was applied with pyridate, injury increased and dry weight decreased linearly. Despite substantial crop injury 7 d after treatment with pyridate alone, pyridate + sethoxydim, and pyridate + COC, yields of field-grown cabbage were reduced significantly in 1 yr only when the three materials were combined. Pyridate injury decreased as time between sethoxydim + COC applications, before and after pyridate was applied, increased.