Disc rheological parameters regulate the mechanical and biological function of intervertebral disc. The knowledge of effects of degeneration on disc rheology can be beneficial for the design of new disc implants or therapy. We developed two material property identification protocols, i.e., inverse poroelas-tic finite element analysis, and biphasic closed form solution. These protocols were used to find the material properties of intact, moderate and severe degenerated porcine discs. Comparing these two computational protocols for intact and artificial degenerated discs showed they are valid in defining bi-phasic/poroelastic properties. We found that enzymatic agent disrupts the functional interactions of proteoglycans which decreased hydraulic permeability and aggregate modulus but increased the Poisson's ratio. The fatigue loading, which damages disc structure, and squeezes and occludes the matrix pores, further decreased the hydraulic permeability and the Poisson's ratio but increased the elastic modulus. The FE simulations showed the stress experienced during the creep test increases with severe degeneration but steady-state fluid loss decreases for the both moderate and severe degenerated discs. Discriminant analysis declared that the probability of correct classification using the FE analysis is higher than the results of the closed form solution. The specimen-specific models extracted from FE analysis can be additionally used for complimentary investigations on disc biomechanics.