The Society of Antiquaries of London holds, under ms 86, an unconventional manuscript described in its catalogue as ‘brief notes on the Kings of Portugal’. The manuscript is in a mid-sixteenth-century hand and has personal annotations by William Cecil (1520–98), better known as Lord Burghley. It recounts the history of Portugal by reigns and belonged to Cecil’s personal library. Until now, no other extant example of a history of Portugal written in English in the sixteenth century was known. This article publishes the first transcription of this unique document, while analysing its contents and explaining its importance. The first section will discuss the history of the manuscript itself, explaining its owners, its likely date of composition and the problems relating to authorship. The second part will deal with the raft of reasons why we believe William Cecil ordered its composition. The third section will detail the major contents of the manuscript, discussing its most interesting details. Finally, the conclusion will reflect on why this manuscript is important for British history.