Let Ω be a smooth bounded domain in RN, with N ≥ 5. We provide existence and bifurcation results for the elliptic fourth-order equation Δ2u − Δpu = f(λ, x, u) in Ω, under the Dirichlet boundary conditions u = 0 and ∇u = 0. Here λ is a positive real number, 1 < p ≤ 2# and f(.,., u) has a subcritical or a critical growth s, 1 < s ≤ 2*, where and . Our approach is variational, and it is based on the mountain-pass theorem, the Ekeland variational principle and the concentration-compactness principle.