Despite numerous biographies, Antonio Lopez de Santa Anna remains one of the most enigmatic characters to have emerged in nineteenth century Latin America. Often dismissed by his many detractors as an unprincipled opportunist in the worst military caudillo tradition, he nevertheless dominated the turbulent and often chaotic Mexican political scene in the thirty years between independence and the Reform. His life has naturally been subjected to close scrutiny by both his contemporaries and more recent historians but his genius for political manouevre and equivocation have left many episodes in his career obscure and subject to doubt. Perhaps nowhere is this more the case than in his first presidency from 1833-1834 and in particular in his relations with his vice-president Gomez Farias' administration. This article seeks to examine his activities and ambitions in these years, and to suggest reasons, which hitherto have been overlooked or at least not given sufficient attention by his biographers, why he chose to betray and destroy the liberals' first attempt at reform.