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Patterns of Salivary Flow in Depressive Illness and During Treatment

Published online by Cambridge University Press:  29 January 2018

G. Palmai
Affiliation:
The Maudsley Hospital, Denmark Hill, London, S.E.5
B. Blackwell
Affiliation:
The Maudsley Hospital, Denmark Hill, London, S.E.5
A. E. Maxwell
Affiliation:
The Maudsley Hospital, Denmark Hill, London, S.E.5
F. Morgenstern
Affiliation:
The Maudsley Hospital, Denmark Hill, London, S.E.5

Extract

The search for objective indices in diagnosis and prognosis of patients suffering from mental illness remains a matter of great clinical interest. While advances in this field have been reported from time to time, no method has become unequivocally established, and in affective disorders much interest has focused on the possible link between mood and physiological change. Cannon's work on the “Bodily Changes in Pain, Hunger, Fear and Rage” (1920) indicated the breadth of this relationship and gave impetus to attempts at rating emotional responses by the severity of their accompanying autonomic changes. Papez (1937) also emphasized that “emotion is such an important function that its mechanism, whatever it be, should be placed on a structural basis”. While this is being sought currently in the limbic system, reticular formation and hypothalamus, the importance of the autonomic system as effector pathway of physiological responses accompanying emotional states has in no way diminished.

Type
Research Article
Copyright
Copyright © Royal College of Psychiatrists, 1967 

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References

Ayd, F. J. (1960). “Amitriptyline therapy for depressive reactions.” Psychosomatic, 1, 320.Google Scholar
Becks, H. (1939). “A study of the rate of flow of resting saliva.” J. dent. Res., 18, 431.Google Scholar
Bernard, , Claude, (1856). Leçons de Physiologie Expérimentale. Paris.Google Scholar
Bogdonoff, M. D., Bogdonoff, M. M., and Stewart, G. W. (1961). “Studies on salivary function in man; variations in secretory rate as part of the individual's adaptive pattern.” J. psychosom. Res., 5, 170.Google Scholar
Bushfield, B. L., and Wechsler, M. (1961). “Studies of salivation in depression.” A.M.A. Arch. gen. Psychiat., 4, 10.Google Scholar
Bushfield, B. L., and Wechsler, M. (1962). “Salivation rate; a physiologic correlate of improvement in hospitalized depressed patients treated with three anti-depressant medications.” Psychosom. Med., 24, 337.Google Scholar
Cannon, W. B. (1920). Bodily Changes in Pain, Hunger, Fear and Rage.New York: Appleton-Century.Google Scholar
Davies, B. M., and Gurland, J. B. (1961). “Salivary secretion in depressive illness.” J. psychosom. Res., 5, 269.Google Scholar
Davies, B. M., and Palmai, G. (1964). “Salivary and blood pressure responses to methacholine in depressive illness.” Brit. J. Psychiat., 110, 594.Google Scholar
Dewar, M. R., and Parfitt, G. J. (1954). “The investigation of the physical properties of saliva and their relationship to the mucin content.” J. dent. Res., 33, 596.Google Scholar
Diamant, H. (1960). “Discussion on the salivary glands, Physiology, Pathology and treatment.” Proc. roy. Soc. Med., 53, 461.Google Scholar
Dobkin, A., and Palko, D. (1960). “The antisialogogue effect of phenothiazine derivatives.” Anaesthesiology, 21, 260.Google Scholar
Emmelin, N. (1952). “On the mechanism of paralytic section.” Acta physiol. Scand., 26, 232.Google Scholar
Erbrino, H. (1936). “Untersuchungen über die Spinnbarkeit flüssiger Systeme.” Kolloid-Beihefte, 44, 171.Google Scholar
Gottlieb, G., Paulson, G., and Raleigh, N. C. (1961). “Salivation in depressed patients.” Arch. gen. Psychiat., 5, 468.Google Scholar
Kurotsu, T., Ban, T., and Masai, H. (1953). “Die Veränderungen im feineren Bau der Speicheldrüsenzellen in Folge elektrischer Reizung des autonomen Zentrums.” Zbl. Hals-, Nas.- u. Ohrenheilk., 46, 39.Google Scholar
Lashley, K. S. (1916). “Reflex secretion of the human parotid gland.” J. exp. Psychol., 1, 461.Google Scholar
Loew, D. (1965). “Syndrom Diagnose und Speichelsekretion bei depressiven Patienten.” Psychopharmacologia, 7, 339.Google Scholar
Lundberg, A. (1958). “Electrophysiology of salivary glands.” Physiol. Rev., 38, 21.Google Scholar
Palmai, G., and Blackwell, B. (1965). “The diurnal pattern of salivary flow in normal and depressed patients.” Brit. J. Psychiat., 111, 334.Google Scholar
Papez, J. W. (1937). “A proposed mechanism of emotion.” Arch. Neurol. Psychiat., 38, 725.Google Scholar
Peck, R. E. (1959). “Salivary secretion in depressive illness.” Arch. gen. Psychiat. (Chic.), 1, 35.Google Scholar
Rauch, S. (1959). Die Speicheldrüsen des Menschen, Stuttgart: G. Thieme.Google Scholar
Rathburn, R. C., and Slater, I. H. (1963). “Amitriptyline and nortriptyline as antagonists of central and peripheral cholinergic activation.” Psychopharmacologia, 4, 114.Google Scholar
Schreyer, L. H., and Levin, L. K. (1955). “Rate of secretion by individual salivary gland pairs of man under conditions of reduced exogenous stimulation.” J. app. Physiol., 7, 508.Google Scholar
Spealman, C. R. (1943). “The volume of flow of resting salivary secretion.” Amer. J. Physiol., 139, 225.Google Scholar
Strongin, E. L., and Hinsie, L. E. (1938). “Parotid gland secretion in manic-depressive patients.” Amer. J. Psychiat., 94, 1459.Google Scholar
Strongin, E. L., and Hinsie, L. E. (1939). “A method for differentiating manic-depressive depressions from other depressions by means of parotid secretions.” Psychiat. Quart., 113, 697.Google Scholar
Sulzer, F., Watts, J. S., and Brodie, B. B. (1961). “Blocking of reserpine action by imipramine, a drug devoid of stimulating effect in normal animals.” Fed. Proc., 20, 321.Google Scholar
Sutherland, G. F. (1958). “The salivary curve—a psychiatric thermometer?Presented at the 114th Annual Meeting of the American Psychiatric Association, San Francisco.Google Scholar
Wainwright, W. W. (1939). “A study of rate of flow of activated saliva.” J. dent. Res., 18, 441.Google Scholar
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