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Course and symptom and functional correlates of passivity symptoms in schizophrenia: an 18-year multi-follow-up longitudinal study

Published online by Cambridge University Press:  16 December 2019

Ellen S. Herbener  and
Martin Harrow
Ellen S. Herbener*
Affiliation:
Department of Psychology, University of Illinois at Chicago, 1007 W Harrison St., Chicago, IL60607, USA Department of Psychiatry, University of Illinois at Chicago, 1601 W Taylor St., Chicago, IL60612, USA
Martin Harrow
Affiliation:
Department of Psychiatry, University of Illinois at Chicago, 1601 W Taylor St., Chicago, IL60612, USA
*
Author for correspondence: Ellen S. Herbener, E-mail: [email protected]
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Abstract

Background

Change in the experience of oneself may lay the groundwork for the development of additional hallucinations and delusions in individuals with schizophrenia. However, to date, the course and symptom and functioning correlates of passivity symptoms (cf. thought insertion, thought withdrawal) have not been measured consistently over long periods of time. Information on the course and correlates of passivity symptoms is essential for developing models of their contribution to schizophrenic illness.

Method

Eighty-two individuals diagnosed with schizophrenia or schizoaffective disorder were recruited at an index hospitalization and reassessed at three or more follow-ups over the following 18 years.

Results

The results indicate that a small group of participants report passivity symptoms at all follow-ups, many reported passivity symptoms at some follow-ups, and the majority of individuals never reported passivity symptoms. The prevalence of passivity symptoms was similar to that for delusions of reference and persecutory delusions. Notably, when individuals did experience passivity symptoms, they also had a greater number of additional psychotic symptoms than individuals without passivity symptoms. Further, the presence of passivity symptoms was associated with work impairment at some assessments.

Conclusions

Passivity symptoms present episodically, at a similar rate as delusions of reference and persecutory delusions, and when present, they are associated with having a higher number of additional psychotic symptoms, as well as having some impact on work functioning. These results suggest that passivity symptoms may increase vulnerability to additional psychotic symptoms and greater work impairment.

Keywords

Anomalous self-experiencedelusionshallucinationspassivity
Type
Original Articles
Information
Psychological Medicine , Volume 51 , Issue 3 , February 2021 , pp. 503 - 510
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Copyright
Copyright © Cambridge University Press 2019

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References

American Psychiatric Association. (1980). Diagnostic and statistical manual of mental disorders (3rd ed., text rev.). Washington, DC: APA.Google Scholar
Basavaraj, R., Mehta, U. M., Thirthalli, J., & Gangadhar, B. N. (2015). Mirror neuron dysfunction and ego-boundary disturbances in schizophrenia: A transcranial magnetic stimulation study. Indian Journal of Psychological Medicine, 37, 58–65.CrossRefGoogle Scholar
Ben-Zeev, D., Morris, S., Swendsen, J., & Granholm, E. (2012). Predicting the occurrence, conviction, distress, and disruption of different delusional experiences in the daily life of people with schizophrenia. Schizophrenia Bulletin, 38, 826–837.CrossRefGoogle ScholarPubMed
Birchwood, M., Smith, J., Cochrane, R., Wetton, S., & Copestake, S. (1990). The Social Functioning Scale. The development and validation of a new scale of social adjustment for use in family intervention programmes with schizophrenic patients. British Journal of Psychiatry, 157, 853–859.CrossRefGoogle ScholarPubMed
Carpenter, W. T. Jr., Sacks, M. H., Strauss, J. S., Bartko, J. J., & Rayner, J. (1976). Evaluating signs and symptoms: comparison of structured interview and clinical approaches. British Journal of Psychiatry, 128, 397–403.CrossRefGoogle ScholarPubMed
Chandrasena, R., & Rodrigo, A. (1979). Schneider's First Rank Symptoms: Their prevalence and diagnostic implications in an Asian population. British Journal of Psychiatry, 135, 348–351.10.1192/bjp.135.4.348CrossRefGoogle Scholar
Deister, A., & Marneros, A. (1993). Long-term stability of subtypes in schizophrenic disorders: a comparison of four diagnostic systems. European Archives of Psychiatry and Clinical Neuroscience, 242, 184–190.CrossRefGoogle ScholarPubMed
Endicott, J., & Spitzer, R. L. (1978). A diagnostic interview: The schedule for affective disorders and schizophrenia. Archives of General Psychiatry, 35, 837–844.CrossRefGoogle Scholar
Fervaha, G., Foussias, G., Agid, O., & Remington, G. (2015). Motivational deficits in early schizophrenia: Prevalent, persistent, and key determinants of functional outcome. Schizophrenia Research, 166, 9–16.CrossRefGoogle ScholarPubMed
Fulford, D., Piskulic, D., Addington, J., Kane, J. M., Schooler, N. R., & Mueser, K. T. (2018). Prospective relationships between motivation and functioning in recovery after a first episode of schizophrenia. Schizophrenia Bulletin, 44, 369–377.CrossRefGoogle ScholarPubMed
Goghari, V. M., & Harrow, M. (2016). Twenty year multi-follow-up of different types of hallucinations in schizophrenia, schizoaffective disorder, bipolar disorder, and depression. Schizophrenia Research, 176, 371–377.10.1016/j.schres.2016.06.027CrossRefGoogle ScholarPubMed
Gonzalez-Pinto, A., van Os, J., Peralta, V., Perez de Heredia, J. L., Mosquera, F., Aldama, A. … Mico, J. A. (2004). The role of age in the development of Schneiderian symptoms in patients with a first psychotic episode. Acta Psychiatrica Scandinavica, 109, 264–268.CrossRefGoogle ScholarPubMed
Graham, K. T., Martin-Iverson, M. T., Holmes, N. P., Jablensky, A., & Waters, F. (2014). Deficits in agency in schizophrenia, and additional deficits in body image, body schema, and internal timing, in passivity symptoms. Frontiers in Psychiatry, 5, 126. doi: 10.3389/fpsyt.2014.00126CrossRefGoogle ScholarPubMed
Green, M. F., Kern, R. S., Braff, D. L., & Mintz, J. (2000). Neurocognitive deficits and functional outcome in schizophrenia: Are we measuring the ‘right stuff’? Schizophrenia Bulletin, 26, 119–136.CrossRefGoogle Scholar
Harrow, M., & Jobe, T. (2013). Does long-term treatment of schizophrenia with antipsychotic medications facilitate recovery? Schizophrenia Bulletin, 39, 962–965.CrossRefGoogle ScholarPubMed
Harrow, M., Jobe, T., Faull, R. N., & Yang, J. (2017). A 20-year multi-followup longitudinal study assessing whether antipsychotic medications contribute to work functioning in schizophrenia. Psychiatry Research, 256, 267–274.CrossRefGoogle Scholar
Haug, E., Oie, M., Andreassen, O. A., Bratlien, U., Raballo, A., Nelson, B. … Melle, I. (2014). Anomalous self-experiences contribute independently to social dysfunction in the early phases of schizophrenia and psychotic bipolar disorder. Comprehensive Psychiatry, 55, 475–482.CrossRefGoogle ScholarPubMed
Heering, H. D., van Haren, N. E., Derks, E. M., & GROUP Investigators. (2013). A two-factor structure of first rank symptoms in patients with a psychotic disorder. Schizophrenia Research, 147, 269–274.CrossRefGoogle ScholarPubMed
Heering, H. D., van Haren, N. E., & GROUP Investigators. (2016). Social functioning in patients with a psychotic disorder and first rank symptoms. Psychiatry Research, 237, 147–152.CrossRefGoogle ScholarPubMed
Herbener, E. S., & Harrow, M. (2001). Longitudinal assessment of negative symptoms in schizophrenia/schizoaffective patients, other psychotic patients, and depressed patients. Schizophrenia Bulletin, 27, 527–537.CrossRefGoogle ScholarPubMed
Herbener, E. S., & Harrow, M. (2004). Are negative symptoms associated with functioning deficits in both schizophrenia and nonschizophrenia patients? A 10-year longitudinal analysis. Schizophrenia Bulletin, 30, 813–825.CrossRefGoogle ScholarPubMed
Jablensky, A. (1992). Schizophrenia: manifestations, incidence and course in different cultures. A World Health Organization ten-country study. Psychological Medicine Monograph Supplement, 20, 1–97.CrossRefGoogle ScholarPubMed
Kaneda, Y., Jayathilak, K., & Meltzer, H. Y. (2009). Determinants of work outcome in schizophrenia and schizoaffective disorder: Role of cognitive function. Psychiatry Research, 169, 178–179.CrossRefGoogle ScholarPubMed
Llerena, K., Reddy, L. F., & Kern, R. S. (2018). The role of experiential and expressive negative symptoms on job obtainment and work outcome in individuals with schizophrenia. Schizophrenia Research, 192, 148–153.CrossRefGoogle ScholarPubMed
Maher, B. A. (2006). The relationship between delusions and hallucinations. Current Psychiatry Reports, 8, 179–183.CrossRefGoogle ScholarPubMed
Mellor, C. S. (1970). First rank symptoms of schizophrenia. I. The frequency in schizophrenics on admission to hospital. II. Differences between individual first rank symptoms. British Journal of Psychiatry, 117, 15–23.CrossRefGoogle Scholar
Mishara, A. L., Lysaker, P. H., & Schwartz, M. A. (2014). Self-disturbances in schizophrenia: History, phenomenology, and relevant findings from research on metacognition. Schizophrenia Bulletin, 40, 5–12.CrossRefGoogle ScholarPubMed
Morcillo, C., Stochl, J., Russo, D. A., Zambrana, A., Ratnayake, N., Jones, P. B. & Perez, J. (2015). First-rank symptoms and premorbid adjustment in young individuals at increased risk of developing psychosis. Psychopathology, 48, 120–126.CrossRefGoogle ScholarPubMed
Nelson, B., Whitford, T. J., Lavoie, S., & Sass, L. A. (2014). What are the neurocognitive correlates of basic self-disturbance in schizophrenia? Integrating phenomenology and neurocognition: Part 2 (aberrant salience). Schizophrenia Research, 152, 20–27.CrossRefGoogle Scholar
Northoff, G. (2014). How is our self altered in psychiatric disorders? A neurophenomenal approach to psychopathological symptoms. Psychopathology, 47, 365–376.CrossRefGoogle Scholar
Parnas, J., Carter, J., & Nordgaard, J. (2016). Premorbid self-disorders and lifetime diagnosis in the schizophrenia spectrum: A prospective high-risk study. Early Interventions in Psychiatry, 10, 45–53.CrossRefGoogle ScholarPubMed
Parnas, J., Handest, P., Jansson, L., & Saebye, D. (2005). Anomalous subjective experience among first-admitted schizophrenia spectrum patients: empirical investigation. Psychopathology, 38, 259–267.CrossRefGoogle ScholarPubMed
Parnas, J., & Henriksen, M. G. (2013). Subjectivity and schizophrenia: Another look at incomprehensibility and treatment nonadherence. Psychopathology, 46, 320–329.CrossRefGoogle Scholar
Pogue-Geile, M. F., & Harrow, M. (1984). Negative and positive symptoms in schizophrenia and depression: A follow-up. Schizophrenia Bulletin, 10, 371–387.CrossRefGoogle Scholar
Pogue-Geile, M. F., & Harrow, M. (1985). Negative symptoms in schizophrenia: Their longitudinal course and prognostic importance. Schizophrenia Bulletin, 11, 427–439.CrossRefGoogle ScholarPubMed
Racenstein, J. M., Harrow, M., Reed, R., Martin, E., Herbener, E., & Penn, D. L. (2002). The relationship between positive symptoms and instrumental work functioning in schizophrenia: A 10 year follow-up study. Schizophrenia Research, 56, 95–103.CrossRefGoogle ScholarPubMed
Ramperti, N., Anwar, M., Renwick, L., Jackson, D., Foley, S., McWilliams, S. … O'Callaghan, E. (2010). First rank symptoms in first episode psychosis and their relationship to the duration of untreated illness. Journal of Nervous and Mental Disease, 198, 820–823.CrossRefGoogle ScholarPubMed
Rocca, P., Montemagni, C., Zappia, S., Pitera, R., Sigaudo, M., & Bogetto, F. (2014). Negative symptoms and everyday functioning in schizophrenia: A cross-sectional study in a real world setting. Psychiatry Research, 218, 284–289.CrossRefGoogle ScholarPubMed
Shepherd, M., Watt, D., Falloon, I., & Smeeton, N. (1989). The natural history of schizophrenia: A five-year follow-up study of outcome and prediction in a representative sample of schizophrenics. Psychological Medicine Monograph Supplement, 15, 1–46.CrossRefGoogle Scholar
Shergill, S. S., Samson, G., Bays, P. M., Frith, C. D., & Wolpert, D. M. (2005). Evidence for sensory prediction deficits in schizophrenia. American Journal of Psychiatry, 162, 2384–2386.CrossRefGoogle Scholar
Sterzer, P., Mishara, A. L., Voss, M., & Heinz, A. (2016). Thought insertion as a self-disturbance: An integration of predictive coding and phenomenological approaches. Frontiers in Human Neuroscience, 10, 502. doi: 10.3389/fnhum.2016.00502CrossRefGoogle ScholarPubMed
Strauss, J., & Carpenter, W. (1972). The prediction of outcome in schizophrenia: I. Characteristics of outcome. Archives of General Psychiatry, 27, 739–746.CrossRefGoogle Scholar
Svendsen, I. H., Oie, M. G., Moller, P., Nelson, B., Melle, I., & Haug, E. (2018). Stability in basic self-disturbances and diagnosis in a first treated psychosis: A seven year follow-up study. Schizophrenia Research, 202, 274–280.CrossRefGoogle Scholar
Tikka, S. K., Nizamie, S. H., Das, A. K., Agarwal, N., & Goyal, N. (2016). Schneiderian first rank symptoms in schizophrenia: A developmental neuroscience evaluation. International Journal of Developmental Neuroscience, 50, 39–46.CrossRefGoogle ScholarPubMed
van Rooijen, G., Isvoranu, A.-M., Meijer, C. J., van Borkulo, C. D., Ruhe, H. G., de Haan, L., GROUP investigators (2017). A symptom network structure of the psychosis spectrum. Schizophrenia Research, 189, 75–83.CrossRefGoogle ScholarPubMed
Waters, F., & Jablensky, A. (2009). Time discrimination deficits in schizophrenia patients with first-rank(passivity) symptoms. Psychiatry Research, 167, 12–20.CrossRefGoogle ScholarPubMed
Whitford, T. J., Ford, J. M., Mathalon, D. H., Kubicki, M., & Shenton, M. E. (2012). Schizophrenia, myelination, and delayed corollary discharges: A hypothesis. Schizophrenia Bulletin, 38, 486–494.CrossRefGoogle ScholarPubMed