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Season of birth for Alzheimer's disease in the Southern Hemisphere

Published online by Cambridge University Press:  09 July 2009

A. S. Henderson ,
A. E. Korten ,
A. F. Jorm ,
E. McCusker ,
H. Creasey  and
G. A. Broe
A. S. Henderson*
Affiliation:
NH & MRC Social Psychiatry Research Unit, The Australian National University, Canberra; Department of Geriatric Medicine, Repatriation General Hospital, Concord, Australia
A. E. Korten
Affiliation:
NH & MRC Social Psychiatry Research Unit, The Australian National University, Canberra; Department of Geriatric Medicine, Repatriation General Hospital, Concord, Australia
A. F. Jorm
Affiliation:
NH & MRC Social Psychiatry Research Unit, The Australian National University, Canberra; Department of Geriatric Medicine, Repatriation General Hospital, Concord, Australia
E. McCusker
Affiliation:
NH & MRC Social Psychiatry Research Unit, The Australian National University, Canberra; Department of Geriatric Medicine, Repatriation General Hospital, Concord, Australia
H. Creasey
Affiliation:
NH & MRC Social Psychiatry Research Unit, The Australian National University, Canberra; Department of Geriatric Medicine, Repatriation General Hospital, Concord, Australia
G. A. Broe
Affiliation:
NH & MRC Social Psychiatry Research Unit, The Australian National University, Canberra; Department of Geriatric Medicine, Repatriation General Hospital, Concord, Australia
*
1Address for correspondence: Professor A. S. Henderson, NH & MRC Social Psychiatry Research Unit, The Australian National University, GPO Box 4. Canberra, ACT 2601, Australia.
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Synopsis

Season of birth was compared in 170 clinically diagnosed cases of Alzheimer's disease (AD) in Australia and 170 matched controls. A further comparison was made with a large population sample of the elderly. No evidence for seasonality of birth was found. This finding held not only for the total series of 170 cases, but also for the 143 born in the Southern Hemisphere, for sporadic cases, and for those with earlier onset. These negative findings in Australia contrast with the positive finding in London by Philpot et al. (1989).

Type
Original Articles
Information
Psychological Medicine , Volume 21 , Issue 2 , May 1991 , pp. 371 - 374
Copyright
Copyright © Cambridge University Press 1991

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References

Australian Bureau of Statistics (1989). June 1988 and Preliminary June 1989 Estimated Resident Population by Country of Birth, Age and Sex, Australia. Australian Bureau of Statistics Catalogue No. 3221.0: Canberra.Google Scholar
Broe, G. A., Henderson, A. S., Creasey, H., McCusker, E., Korten, A. E., Jorm, A. F., Longley, W. & Anthony, J. C. (1991). A case-control study of Alzheimer's disease in Australia. Neurology (in the press).Google Scholar
Cohen, J. (1977). Statistical Power Analysis for the Behavioral Sciences. Academic Press: New York.Google Scholar
Edwards, J. H. (1961). The recognition and estimation of cyclic trends. Annals of Human Genetics 25, 83–86.CrossRefGoogle ScholarPubMed
Folstein, M. F., Folstein, S. E. & McHugh, P. R. (1975). ‘Mini-Mental State’: a practical method for grading the cognitive state of patients for the clinician. Journal of Psychiatric Research 12, 189–198.CrossRefGoogle Scholar
Henderson, A. S. (1989). The risk factors for Alzheimer's disease: a review and a hypothesis. Acta Psychiatrica Scandinavica 78, 257–275.CrossRefGoogle Scholar
Jorm, A. F. (1990). The Epidemiology of Alzheimer's Disease and Related Disorders. Chapman and Hall: London.Google Scholar
McKhann, G., Drachman, D., Folstein, M., Katzman, R., Price, D. & Stadlan, E. M. (1984). Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 34, 939–944.CrossRefGoogle ScholarPubMed
Philpot, M., Rottenstein, M., Alistair, B. & Der, G. (1989). Season of birth in Alzheimer's disease. British Journal of Psychiatry 155, 662–666.CrossRefGoogle ScholarPubMed
Roger, J. H. (1977). A significance test for cyclic trends in incidence data. Biometrika 64, 152–155.CrossRefGoogle Scholar