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The nature of resistance of immune puppies to superinfection with Toxocara canis: evidence that immunity affects second- but not fourth-stage larvae
Published online by Cambridge University Press: 06 April 2009
Extract
Fourth-stage larvae of Toxocara canis were introduced directly into the intestine of previously immunized puppies after laparotomy. They developed normally to the adult stage. In general 46–60% of the introduced larvae completed their development. By contrast the second-stage larvae introduced into similarly immunized puppies did not develop any further. No fourth-stage larvae or adult stages were noted in the nonimmunized controls. The post-immunization sera of puppies formed precipitates at the oral orifices of the second-stage but not of the fourth-stage larvae and antibody response was detected following infection with large doses of infective ova but not small doses of infective ova or fourth-stage larvae.
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- Copyright © Cambridge University Press 1973
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