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Thermal and in vitro evaluation of a composite material pHEMA/Chitosan/Hydroxyapatite

Published online by Cambridge University Press:  16 March 2015

Areli.M. Salgado-Delgado ,
Zully Vargas-Galarza ,
René Salgado-Delgado ,
Efraín Rubio-Rosas ,
Edgar García-Hernández  and
Wendy. N. Hernández-Díaz
Areli.M. Salgado-Delgado
Affiliation:
División de Estudios de Posgrado e Investigación/Departamento de Ing. Química y Bioquímica, Instituto Tecnológico de Zacatepec, Calzada Tecnológico No. 27, Zacatepec, Morelos, C.P. 62780, México
Zully Vargas-Galarza
Affiliation:
División de Estudios de Posgrado e Investigación/Departamento de Ing. Química y Bioquímica, Instituto Tecnológico de Zacatepec, Calzada Tecnológico No. 27, Zacatepec, Morelos, C.P. 62780, México
René Salgado-Delgado
Affiliation:
División de Estudios de Posgrado e Investigación/Departamento de Ing. Química y Bioquímica, Instituto Tecnológico de Zacatepec, Calzada Tecnológico No. 27, Zacatepec, Morelos, C.P. 62780, México
Efraín Rubio-Rosas
Affiliation:
Centro Universitario de Vinculación y Transferencia de Tecnología, Benemérita Universidad Autónoma de Puebla, Prolongación de la 24 Sur y av. San Claudio, Ciudad Universitaria, Col. San Manuel, Puebla, Puebla, C. P. 72570, México.
Edgar García-Hernández
Affiliation:
División de Estudios de Posgrado e Investigación/Departamento de Ing. Química y Bioquímica, Instituto Tecnológico de Zacatepec, Calzada Tecnológico No. 27, Zacatepec, Morelos, C.P. 62780, México
Wendy. N. Hernández-Díaz
Affiliation:
División de Estudios de Posgrado e Investigación/Departamento de Ing. Química y Bioquímica, Instituto Tecnológico de Zacatepec, Calzada Tecnológico No. 27, Zacatepec, Morelos, C.P. 62780, México
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Abstract

Bioactive materials based on polymer/hydroxyapatite are currently being extensively investigated as materials for promotion of bone tissue regeneration and reconstruction [1]. In this work, a material interpenetrating based on poly 2-hydroxyethyl methacrylate (pHEMA), Chitosan and hydroxyapatite (HA) was prepared following the methodology of the foaming gas Damla Çetin [2], generating an interpenetrated network with the chitosan filled with hydroxyapatite. The materials were evaluated by thermal gravimetric analysis (TGA) and in vitro bioactivity [3] (SBF) and characterized by using scanning electron microscopy (SEM). The TGA studies suggested that there was not existence of possible interactions between polymers and HA but there is a thermal stability increase in the HA content. Meanwhile, SBF and its characterization by SEM, was found that the materials are bioactives as indicated by the formation of a bone-like apatite layer after immersion in simulated body fluid, indicating the potential of this material for use in bone tissue engineering.

Keywords

compositebiomedicalthermogravimetric analysis (TGA)
Type
Articles
Information
MRS Online Proceedings Library (OPL) , Volume 1767: Symposium 5C – New Trends in Polymer Chemistry and Characterization , 2015 , pp. 133 - 138
Copyright
Copyright © Materials Research Society 2015 

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References

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