Hostname: page-component-586b7cd67f-rcrh6 Total loading time: 0 Render date: 2024-11-28T13:17:41.125Z Has data issue: false hasContentIssue false
  • English
  • Français

Preparation and Properties of Silica-Coated AgI Nanoparticles with a Modified Stober Method

Published online by Cambridge University Press:  01 February 2011

Yoshio Kobayashi ,
Kiyoto Misawa ,
Motohiro Takeda ,
Noriaki Ohuchi ,
Atsuo Kasuya  and
Mikio Konno
Yoshio Kobayashi
Affiliation:
[email protected], Ibaraki University, College of Engineering, 4-12-1 Naka-narusawa-cho, Hitachi, Ibaraki, 316-8511, Japan, +81-294-38-5052, +81-294-38-5078
Kiyoto Misawa
Affiliation:
[email protected], Tohoku University, Graduate School of Engineering, Sendai, 980-8579, Japan
Motohiro Takeda
Affiliation:
[email protected], Tohoku University, Graduate School of Medicine, Sendai, 980-8574, Japan
Noriaki Ohuchi
Affiliation:
[email protected], Tohoku University, Graduate School of Medicine, Sendai, 980-8574, Japan
Atsuo Kasuya
Affiliation:
[email protected], Tohoku University, Center for Interdisciplinary Research, Sendai, 980-8578, Japan
Mikio Konno
Affiliation:
[email protected], Tohoku University, Graduate School of Engineering, Sendai, 980-8579, Japan
Get access

Abstract

Iodine compounds have been used as X-ray contrast agents in the field of medicine, because of their low transmittance property for X-ray. The iodine compounds may provoke adverse events as allergic reactions in patients, so that they can not be administered to such people. Core-shell nanoparticles are good candidates for prevention of allergic reactions, because the shell materials can keep the contrast agents from living systems. We have proposed a method for silica-coating of iodine compounds as AgI nanoparticles. In the present work, properties of the silica-coated AgI nanoparticles such as colloidal stability, X-ray absorption and X-ray CT imaging were examined.

Silica-coated AgI nanoparticles were prepared with Stöber method, which was performed with 2.3×10-5 M MPS, 11 M water, 0.01 M DMA and 0.01 M tetraethyl orthosilicate in the presence of 5×10-4 M AgI nanoparticles that were prepared from AgClO4 and KI. The particles had an AgI core size of ca. 15 nm and a silica shell thickness of ca. 20 nm.

Since high iodine concentration in sample solution is desired for practical use as X-ray contrast agents, the colloid of as-prepared coated particles was concentrated with centrifugation. The particle colloid that was concentrated up to an AgI concentration as high as 0.4 M was colloidally stable in saline, and exhibited properties of X-ray absorption and X-ray contrasting comparable to a commercial X-ray contrast agent. Accordingly, the silica-coated AgI nanoparticles prepared in the present work are expected to be applied to a novel X-ray contrast agent.

Keywords

particulatecore/shellsol-gel
Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 1074: Symposium I – Synthesis and Metrology of Nanoscale Oxides and Thin Films , 2008 , 1074-I10-07
Copyright
Copyright © Materials Research Society 2008

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

1. Joubert, A. Biston, M.-C., Boudou, C. Ravanat, J.-L., Brochard, T. Charvet, A.-M., Estève, F., Balosso, J. and Foray, N. Int. J. Radiation Oncology Biol. Phys. 62, 1486 (2005).Google Scholar
2. Liz-Marzán, L. M., Giersig, M. and Mulvaney, P. Langmuir, 12, 4329 (1996).Google Scholar
3. Correa-Duarte, M. A., Giersig, M. and Liz-Marzán, L. M., Chem. Phys. Lett., 286, 497 (1998).Google Scholar
4. Ung, T. Liz-Marzán, L. M., and Mulvaney, P. Langmuir, 14, 3740 (1998).Google Scholar
5. Kobayashi, Y. and Liz-Marzán, L. M., Stud. Surf. Sci. Catal., 132, 363 (2001).Google Scholar
6. Kobayashi, Y. Correa-Duarte, M. A., Liz-Marzán, L. M., Langmuir, 17, 6375 (2001).Google Scholar
7. Kobayashi, Y. Horie, M. Konno, M. Rodríguez-González, B., and Liz-Marzán, L. M., J. Phys. Chem. B, 107, 7420 (2003).Google Scholar
8. Mine, E. Yamada, A. Kobayashi, Y. Konno, M. and Liz-Marzán, L. M., J. Colloid Interface Sci., 264, 385 (2003).Google Scholar
9. Kobayashi, Y. Katakami, H. Mine, E. Nagao, D. Konno, M. and Liz-Marzán, L. M., J. Colloid Interface Sci., 283, 392 (2005).Google Scholar
10. Kobayashi, Y. Horie, M. Nagao, D. Ando, Y. Miyazaki, T. and Konno, M. Mater. Lett., 60, 2046 (2006).Google Scholar
11. Park, Y.-S., Liz-Marzán, L. M., Kasuya, A. Kobayashi, Y. Nagao, D. Konno, M. Mamykin, S. Dmytruk, A. Takeda, M. and Ohuchi, N. J. Nanosci. Nanotechnol., 6, 3503 (2006).Google Scholar
12. Kobayashi, Y. and Sakuraba, T. Colloids Surfaces A, 317, 756 (2008).Google Scholar
13. Kobayashi, Y. Misawa, K. Takeda, M. Kobayashi, M. Satake, M. Kawazoe, Y. Ohuchi, N. Kasuya, A. and Konno, M. Colloids Surfaces A, 251, 197 (2004).Google Scholar
14..Kobayashi, Y. Misawa, K. Takeda, M. Ohuchi, N. Kasuya, A. and Konno, M. Adv. Mater. Res., 29-30, 191 (2007).Google Scholar
15..Vogelsang, H. Husberg, O. and Osten, W. Von der, J. Lumin., 86, 87 (2000).Google Scholar
16. Kondo, S. Itoh, T. and Saito, T. Phys. Rev. B, 57, 13235 (1998).Google Scholar
17. Kumar, P. S. Dayal, P. B. Sunandana, C. S. Thin Solid Films, 357, 111 (1999).Google Scholar
18. Wang, Y. Mo, J. Cai, W. Yao, L. and Zhang, L. Mater. Lett., 56, 502 (2002).Google Scholar