No CrossRef data available.
Article contents
Directly Reading The Genome
Published online by Cambridge University Press: 14 March 2018
Extract
Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.
The code for the human genome is essentially complete, opening an expansive book about our biologic composition. But the problem is to read this book. The font size is very small, What you are reading now is 9 point font, and genetic information would correspond to approximately 10-50 point font, six orders of magnitude smaller. There are methods to derive genetic information, but recently Adam Woolley, Chantal Guillemette, Chin-Li Cheung, David Housman, and Charles Lieber have developed an elegant way to directly read genetic information with a microscope. The microscope they used was an atomic force microscope (AFM) that employed a single-walled carbon nanotube as its probe.
- Type
- Research Article
- Information
- Copyright
- Copyright © Microscopy Society of America 2001
Footnotes
1
The authors gratefully acknowledge Dr. Adam Woolley for reviewing this article.
References
Notes
2 Woolley, A.T., Guillemette, C., Cheung, C.L., Housman, D.E., and Lieber, CM., Direct haplotyping of kilobase-size DNA using carbon nanotube probes, Nature Biotechnology 18:760-763, 2000.Google Scholar
You have
Access