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Tissue Response to Bone Substitute Materials Supporting Dental Implants

Published online by Cambridge University Press:  02 July 2020

K. E. Krizan ,
D. Lew ,
T. Rubey  and
J. C. Keller
K. E. Krizan
Affiliation:
Dept. of Oral & Maxillofacial Surgery and Dows Institute for Dental Research, College of Dentistry, The University of Iowa, Iowa City, IA52242
D. Lew
Affiliation:
Dept. of Oral & Maxillofacial Surgery and Dows Institute for Dental Research, College of Dentistry, The University of Iowa, Iowa City, IA52242
T. Rubey
Affiliation:
Dept. of Oral & Maxillofacial Surgery and Dows Institute for Dental Research, College of Dentistry, The University of Iowa, Iowa City, IA52242
J. C. Keller
Affiliation:
Dept. of Oral & Maxillofacial Surgery and Dows Institute for Dental Research, College of Dentistry, The University of Iowa, Iowa City, IA52242
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Extract

The purpose of this study was to evaluate the biological response of a bone substitute material placed around Ti dental implants surgically positioned in tooth extraction sites of canine mandible. Under general anesthesia six adult mongrel canine had bilateral extractions of the fourth premolarbicuspid. Each extraction site was modeled into a 4 wall defect with box-like dimensions (1.0 mm vertically x 1.2 mm horizontally x 0.75 mm laterally). Utilizing the Branemark technique, screwtype implants with healing screws (10 mm x 4 mm), were placed in the prepared sites. A synthetic hydroxyapatite bone cement (HAC) [BoneSource®, Howmedica Laboratories, Inc.] was prepared and filled in around each implant. As controls, three canine had HAC placed in prepared sites without implants. Prior to periodontal flap suture closure a n-butyl-2-cyanoacrylate biodegradable tissue adhesive [Histoacryl®], was placed over implants and HAC. One canine each was euthanized at one month (m), two m, and three m postop.

Type
Pathology
Information
Microscopy and Microanalysis , Volume 4 , Issue S2: Proceedings: Microscopy & Microanalysis '98, Microscopy Society of America 56th Annual Meeting, Microbeam Analysis Society 32nd Annual Meeting, Atlanta, Georgia July 12-16, 1998 , July 1998 , pp. 1092 - 1093
Copyright
Copyright © Microscopy Society of America

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References

References:

1.Branemark, P.-I. et al., in Tissue-Integrated Prostheses Osseointegration in Clinical Dentistry, Chicago: Quintessence Publishing (1985).Google Scholar
2.Spurr, A., J. Ultrastructure Res. 26 (1969) 31.CrossRefGoogle Scholar
3. Support by Center for Oral and Maxillofacial Implants at The University of Iowa and Howmedica-Leibinger, Inc.Google Scholar