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Structure of the Full-Length TRPV2 Channel by Cryo-EM

Published online by Cambridge University Press:  25 July 2016

Kevin W. Huynh ,
Matthew R. Cohen ,
Jiansen Jiang ,
Amrita Samanta ,
David T. Lodowski ,
Z. Hong Zhou  and
Vera Y. Moiseenkova-Bell
Kevin W. Huynh
Affiliation:
Department of Pharmacology, School of Medicine, Case Western Reservere University, Cleveland, Ohio 44106, USA
Matthew R. Cohen
Affiliation:
Department of Pharmacology, School of Medicine, Case Western Reservere University, Cleveland, Ohio 44106, USA Department of Physiology and Biophysics, School of Medicine, Case Western Reservere University, Cleveland, Ohio 44106, USA
Jiansen Jiang
Affiliation:
Department of Microbiology, Immunology and Molecular Genetics, University of California Los Angeles, Los Angeles, California 90095, USA California NanoSystems Institute, University of California Los Angeles, Los Angeles, California 90095, USA
Amrita Samanta
Affiliation:
Department of Pharmacology, School of Medicine, Case Western Reservere University, Cleveland, Ohio 44106, USA Department of Physiology and Biophysics, School of Medicine, Case Western Reservere University, Cleveland, Ohio 44106, USA
David T. Lodowski
Affiliation:
Department of Pharmacology, School of Medicine, Case Western Reservere University, Cleveland, Ohio 44106, USA Department of Nutrition, School of Medicine, Case Western Reservere University, Cleveland, Ohio 444106, USA
Z. Hong Zhou
Affiliation:
Department of Microbiology, Immunology and Molecular Genetics, University of California Los Angeles, Los Angeles, California 90095, USA California NanoSystems Institute, University of California Los Angeles, Los Angeles, California 90095, USA
Vera Y. Moiseenkova-Bell
Affiliation:
Department of Pharmacology, School of Medicine, Case Western Reservere University, Cleveland, Ohio 44106, USA Department of Physiology and Biophysics, School of Medicine, Case Western Reservere University, Cleveland, Ohio 44106, USA

Abstract

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Type
Abstract
Information
Microscopy and Microanalysis , Volume 22 , Supplement S3: Proceedings of Microscopy & Microanalysis 2016 , July 2016 , pp. 1118 - 1119
Copyright
© Microscopy Society of America 2016 

References

References:

[1] Venkatachalam, K. & Montell, C. “TRP channels”. Annu Rev Biochem 76 (2007). pp 387–417.Google Scholar
[2] Smani, T., Shapovalov, G., Skryma, R., Prevarskaya, N. & Rosado, JA. “Functional and physiopathological implications of TRP channels”. Biochimca et Biophysica Acta 1853 (2015). pp 1772–1782.Google Scholar
[3] Liao, M., Cao, E., Julius, D. & Cheng, Y. “Structure of the TRPV1 ion channel determined by electron cryo-microscopy”. Nature 504 (2013). pp 107–112.Google Scholar
[4] Cao, E., Liao, M, Cheng, Y. & Julius, D. “TRPV1 structure in distinct conformations reveal activation mechanisms”. Nature 504 (2013). pp 113–118.Google Scholar
[5] Zheng, J. & Ma, L. “Structure and function of the thermoTRP channel pore”. Curr Top Membr 74 (2014). pp 233–257.Google Scholar