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Structural Rearrangements in R432A Variant of AAV2 Affect Genome Packaging

Published online by Cambridge University Press:  25 July 2016

Lauren M. Drouin ,
Bridget Lins ,
Mandy Janssen ,
Antonette Bennett ,
Paul R. Chipman ,
Robert McKenna ,
Weijun Chen ,
Nicholas Muzyczka ,
Giovanni Cardone  and
Timothy S. Baker
...Show all authors
Lauren M. Drouin
Affiliation:
Department of Biochemistry & Molecular Biology, Center for Structural Biology, The McKnight Brain Institute, College of Medicine, University of Florida, Gainesville, FL, USA
Bridget Lins
Affiliation:
Department of Biochemistry & Molecular Biology, Center for Structural Biology, The McKnight Brain Institute, College of Medicine, University of Florida, Gainesville, FL, USA
Mandy Janssen
Affiliation:
Department of Chemistry and Biochemistry, and Division of Biological Sciences, University of California—San Diego, San Diego, California, USA
Antonette Bennett
Affiliation:
Department of Biochemistry & Molecular Biology, Center for Structural Biology, The McKnight Brain Institute, College of Medicine, University of Florida, Gainesville, FL, USA
Paul R. Chipman
Affiliation:
Department of Biochemistry & Molecular Biology, Center for Structural Biology, The McKnight Brain Institute, College of Medicine, University of Florida, Gainesville, FL, USA
Robert McKenna
Affiliation:
Department of Biochemistry & Molecular Biology, Center for Structural Biology, The McKnight Brain Institute, College of Medicine, University of Florida, Gainesville, FL, USA
Weijun Chen
Affiliation:
Department of Molecular Genetics and Microbiology, University of Florida Genetics Institute, College of Medicine, University of Florida, Gainesville, FL, USA
Nicholas Muzyczka
Affiliation:
Department of Molecular Genetics and Microbiology, University of Florida Genetics Institute, College of Medicine, University of Florida, Gainesville, FL, USA
Giovanni Cardone
Affiliation:
Department of Chemistry and Biochemistry, and Division of Biological Sciences, University of California—San Diego, San Diego, California, USA
Timothy S. Baker
Affiliation:
Department of Chemistry and Biochemistry, and Division of Biological Sciences, University of California—San Diego, San Diego, California, USA
Mavis Agbandje-McKenna
Affiliation:
Department of Biochemistry & Molecular Biology, Center for Structural Biology, The McKnight Brain Institute, College of Medicine, University of Florida, Gainesville, FL, USA

Abstract

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Abstract
Information
Microscopy and Microanalysis , Volume 22 , Supplement S3: Proceedings of Microscopy & Microanalysis 2016 , July 2016 , pp. 1134 - 1135
Copyright
© Microscopy Society of America 2016 

References

References:

[1] Asokan, A, Scaffer, DV & Samulski, RJ Mol Ther 20 (2012) 699–708.Google Scholar
[2] Chapman, M & Agbandje-McKenna, M in “Parvoviruses” (ed. Ker, JR et al, Edward Arnold Ltd, NY.Google Scholar
[3] Grimm, D., et al., Gene Ther 6 (1999) 1322–1330.Google Scholar
[4] Wu, P., et al., J Virol 74 (2000) 8634–8647.Google Scholar
[5] Bleker, S, Pawlitta, M & Kleinschmidt, JA J Virol 80 (2006) 810–820.CrossRefGoogle Scholar
[6] Warrington, , et al., J Virol 78 (2004) 6595–6609.CrossRefGoogle Scholar
[7] Emsley, P., et al., Acta Cryst. D 66 (2010) 486–501.CrossRefGoogle Scholar
[8] Kronenberg, S., et al., J. Virol. 79 (2005) 5296–5303.CrossRefGoogle Scholar
[9] Nam, H.J., et al., J. Virol. 81 (2007) 12260–12271.CrossRefGoogle Scholar
[10] Funding provided by NIH P01 HL51811, R01 AI1081961, R-37 GM033050, Training Grant T32-GM008799, support from the University of California San Diego, and the Agouron Foundation to establish the cryoTEM facilities used in this study.Google Scholar