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Influence of the (citric acid/calcium) ratio on Hap particles synthesis

Published online by Cambridge University Press:  21 August 2009

C. Santos ,
M. Martins ,
M. M. Almeida  and
M. E. V. Costa
C. Santos
Affiliation:
Department of Ceramic and Glass Engineering, CICECO, University of Aveiro, 3810-193 Aveiro, Portugal
M. Martins
Affiliation:
Department of Chemistry, CICECO, University of Aveiro, 3810-193 Aveiro, Portugal.
M. M. Almeida
Affiliation:
Department of Ceramic and Glass Engineering, CICECO, University of Aveiro, 3810-193 Aveiro, Portugal
M. E. V. Costa
Affiliation:
Department of Ceramic and Glass Engineering, CICECO, University of Aveiro, 3810-193 Aveiro, Portugal

Abstract

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Calcium phosphate (CaP) particles aimed at specific applications including dental defect filling, bone tissue engineering and drug delivery may be engineered by different methods based on solution chemical precipitation. The understanding of CaP particle morphology evolution during precipitation is of great scientific interest not only from a fundamental point of view but also because morphology directly or indirectly determines the applicability of the particle. Citrate ion, widely known as a minor bone component, plays an important role as crystal habit modifier and crystal growth inhibitor. However the prediction of CaP growth morphologies in presence of citrate ion is still a challenging issue because the mechanism of citrate and CaP interactions is not yet clearly understood.

Type
Materials Sciences
Information
Microscopy and Microanalysis , Volume 15 , Supplement S3 , July 2009 , pp. 85 - 86
Copyright
Copyright © Microscopy Society of America 2009