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Identification of Scavenger Receptor Sr-Bi in The Endothelial Cells and the Smooth Muscle Cells of Rat Aorta in Vitro and in Vivo

Published online by Cambridge University Press:  02 July 2020

Y P. Liu ,
Y. C. Yeh  and
V. C. Yang
Y P. Liu
Affiliation:
Department of Biology, Tunghai University, Taichung, Taiwan, R.O.C
Y. C. Yeh
Affiliation:
Department of Biology, Tunghai University, Taichung, Taiwan, R.O.C
V. C. Yang
Affiliation:
Department of Biology, Tunghai University, Taichung, Taiwan, R.O.C
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Extract

The class B, type I scavenger receptor (SR-BI) was the first molecularly well defined cell surface receptor which binds HDL and mediates the selective uptake of HDL cholesteryl ester. It is expressed primarily in liver and steroidogenic tissues. However, the recent studies also suggested a potentially important role of SR-BI in the initial steps of cholesterol efflux in the peripheral tissues. In this study, we have used immunofluorescence and immunoelectron microscopy to study the expression and subcellular localization of SR-BI in the endothelial cells and the smooth muscle cells of rat aorta in vitro and in vivo.

Type
Biological Specimen Preparation/Cytochemistry/ Immunolabeling/Immunocytochemistry
Information
Microscopy and Microanalysis , Volume 6 , Issue S2: Proceedings: Microscopy & Microanalysis 2000, Microscopy Society of America 58th Annual Meeting, Microbeam Analysis Society 34th Annual Meeting, Microscopical Society of Canada/Societe de Microscopie de Canada 27th Annual Meeting, Philadelphia, Pennsylvania August 13-17, 2000 , August 2000 , pp. 484 - 485
Copyright
Copyright © Microscopy Society of America

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References

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