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Freeze Substitution and Low Temperature Processing of Cryo Protected Tissues into Lowicryl HM23 Resin for Correlated Light and Immunogold Electron Microscopy in Drug Discovery and Safety Assessment Research

Published online by Cambridge University Press:  22 July 2022

Mike Reichelt ,
Anand Kumar Katakam  and
Meredith Sagolla
Mike Reichelt*
Affiliation:
Genentech, Research Pathology, Center for Advanced Light and Electron Microscopy, South San Francisco, CA, USA
Anand Kumar Katakam
Affiliation:
Genentech, Research Pathology, Center for Advanced Light and Electron Microscopy, South San Francisco, CA, USA
Meredith Sagolla
Affiliation:
Genentech, Research Pathology, Center for Advanced Light and Electron Microscopy, South San Francisco, CA, USA
*
*Corresponding author: [email protected]

Abstract

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Type
Challenges and Advances in Electron Microscopy Research and Diagnosis of Diseases in Humans, Plants and Animals
Information
Microscopy and Microanalysis , Volume 28 , Supplement S1 , August 2022 , pp. 1392 - 1393
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Copyright
Copyright © Microscopy Society of America 2022

References

Carleman, E, et al. , J Microsc. 140 (1985), p. 55-63. doi: 10.1111/j.1365-2818.1985.tb02660.x.CrossRefGoogle Scholar
Johnson, E, et al., Sci Rep. 5 (2015), p. 9583. doi: 10.1038/srep09583.Google Scholar