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Development of an Algorithm for Automatic Image Detection of Biological Particles in Transmission Electron Microscopy Images

Published online by Cambridge University Press:  28 September 2012

M. C. Proença
Affiliation:
Laboratório de Óptica, Lasers e Sistemas, Faculdade de Ciências da Universidade de Lisboa, Ed. C8, 1749-016 Lisboa Centro de Estudos do Ambiente e do Mar, Faculdade de Ciências da Universidade de Lisboa, Ed. C8, 1749-016 Lisboa
J. F. Moura Nunes
Affiliation:
Laboratório de Microscopia Electrónica, Instituto Português de Oncologia, Rua Prof. Lima Basto, 1099-023 Lisboa
A. P. Alves de Matos
Affiliation:
Centro de Estudos do Ambiente e do Mar, Faculdade de Ciências da Universidade de Lisboa, Ed. C8, 1749-016 Lisboa Serviço de Anatomia Patológica, Hospital Curry Cabral, Rua da Beneficência 8, 1069-166 Lisboa

Abstract

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Automatic image processing of transmission electron microscopy images (TEM) is a utopia often pursued, considering the thousands of images necessary to ensure a high resolution 3D reconstruction of virus particles or other macromolecular machines.

Type
Life Sciences
Copyright
Copyright © Microscopy Society of America 2012