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Assessment of Medicago Based Systems for the Production of Human Proteins: Microscopy Analysis of the Subcellular Deposition Patterns of the Recombinant Product

Published online by Cambridge University Press:  28 September 2012

R.B. Santos ,
A.S. Pires ,
H.S. Silva  and
and R. Abranches
R.B. Santos
Affiliation:
Plant Cell Biology Laboratory, Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, Av República, Apt 127, 2781-901 Oeiras, Portugal
A.S. Pires
Affiliation:
Plant Cell Biology Laboratory, Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, Av República, Apt 127, 2781-901 Oeiras, Portugal
H.S. Silva
Affiliation:
Plant Cell Biology Laboratory, Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, Av República, Apt 127, 2781-901 Oeiras, Portugal
and R. Abranches
Affiliation:
Plant Cell Biology Laboratory, Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, Av República, Apt 127, 2781-901 Oeiras, Portugal

Abstract

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The use of transgenic plants for the large scale production of recombinant proteins with commercial and therapeutic value has emerged as an alternative to conventional platforms. Plant based systems, including whole plants and plant cell cultures offer many advantages particularly regarding safety and cost effectiveness. In our laboratory we have been using the model plant Medicago truncatula as a system to express recombinant proteins with a variety of applications.

Type
Life Sciences
Information
Microscopy and Microanalysis , Volume 18 , Supplement S5: Portuguese Supplement , August 2012 , pp. 11 - 12
Copyright
Copyright © Microscopy Society of America 2012