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Porous Vycor Glass as a Model System for Biodevices: An AFM Study of Properties of Water in Confined Geometries

Published online by Cambridge University Press:  02 July 2020

Arjan P. Quist  and
Ratnesh Lal
Arjan P. Quist
Affiliation:
Neuroscience Research Institute, University of California, Santa Barbara, CA, 93106, USA
Ratnesh Lal
Affiliation:
Center for Surface Biotechnology, Uppsala University, Box 577, S-75123, Uppsala, Sweden
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Abstract

Structural and dynamic studies of the adsorption behavior of small molecules within and on the surface of porous systems are of great interest for designing biocompatible and sustainable biodevices. Porous vycor glass is an ideal system for such studies because of its well characterized hydrophilic network of cylindrical pores. Moreover, the pore sizes in vycor are directly comparable to pore sizes of systems like macromolecules and biological membranes. Molecular dynamics simulations of vycor-water interactions as well as some structural data from neutron scattering and diffraction experiments are available. Close to the pore surface the number of water-water hydrogen bonds is reduced, and compensated by vycor-water hydrogen bonds. Insight into the behavior of water molecules in those confined geometries could provide necessary and relevant information for designing biodevices for tissue generation, as well as about contamination- and inflammation affinities of implant materials.

Here we present an Atomic Force Microscopy (AFM) study of vycor at different levels of surface hydration.

Type
Advances in Imaging Techniques for Biomaterlals (Organized by S. Eppel)
Information
Microscopy and Microanalysis , Volume 7 , Issue S2: Proceedings: Microscopy & Microanalysis 2001, Microscopy Society of America 59th Annual Meeting, Microbeam Analysis Society 35th Annual Meeting, Long Beach, California August 5-9, 2001 , August 2001 , pp. 118 - 119
Copyright
Copyright © Microscopy Society of America 2001

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References

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