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Imaging the Cardiovascular System: Seeing Is Believing

Published online by Cambridge University Press:  12 May 2005

Thomas K. Borg ,
James A. Stewart  and
Michael A. Sutton
Thomas K. Borg
Affiliation:
Department of Cell and Developmental Biology and Anatomy, University of South Carolina, Columbia, SC 29208, USA
James A. Stewart
Affiliation:
Department of Cell and Developmental Biology and Anatomy, University of South Carolina, Columbia, SC 29208, USA
Michael A. Sutton
Affiliation:
Department of Mechanical Engineering, University of South Carolina, Columbia, SC 29208, USA
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Abstract

From the basic light microscope through high-end imaging systems such as multiphoton confocal microscopy and electron microscopes, microscopy has been and will continue to be an essential tool in developing an understanding of cardiovascular development, function, and disease. In this review we briefly touch on a number of studies that illustrate the importance of these forms of microscopy in studying cardiovascular biology. We also briefly review a number of imaging modalities such as computed tomography, (CT) Magnetic resonance imaging (MRI), ultrasound, and positron emission tomography (PET) that, although they do not fall under the realm of microscopy, are imaging modalities that greatly complement microscopy. Finally we examine the role of proper imaging system calibration and the potential importance of calibration in understanding biological tissues, such as the cardiovascular system, that continually undergo deformation in response to strain.

Keywords

microscopycardiovascularultrasoundconfocal microscopy
Type
Research Article
Information
Microscopy and Microanalysis , Volume 11 , Issue 3 , June 2005 , pp. 189 - 199
Copyright
© 2005 Microscopy Society of America

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References

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