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Social Cognition Abilities in Patients With Different Multiple Sclerosis Subtypes

Published online by Cambridge University Press:  28 June 2017

Audrey Henry ,
Ayman Tourbah ,
Marie-Pierre Chaunu ,
Serge Bakchine  and
Michèle Montreuil
Audrey Henry*
Affiliation:
Cognition, Health and Socialization lab, University of Reims Champagne-Ardenne, Reims, France Psychopathology and Neuropsychology lab, University of Paris 8, Saint-Denis, France
Ayman Tourbah
Affiliation:
Psychopathology and Neuropsychology lab, University of Paris 8, Saint-Denis, France Reims University Hospital and Reims Faculty of Medicine, University of Reims Champagne-Ardenne, Reims, France
Marie-Pierre Chaunu
Affiliation:
Reims University Hospital and Reims Faculty of Medicine, University of Reims Champagne-Ardenne, Reims, France
Serge Bakchine
Affiliation:
Reims University Hospital and Reims Faculty of Medicine, University of Reims Champagne-Ardenne, Reims, France
Michèle Montreuil
Affiliation:
Psychopathology and Neuropsychology lab, University of Paris 8, Saint-Denis, France
*
Correspondence and reprint requests to: Audrey Henry, Université Reims Champagne-Ardenne, B.P. 30, 57 Rue Pierre Taittinger, 51 571, Reims Cedex, France. E-mail: [email protected]
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Abstract

Objectives: Multiple sclerosis (MS) can be associated with impaired social cognition. However, social cognition skills have never been explored in the different subtypes of MS. The first aim of this study was to examine whether MS subtypes differ on the course of social cognition. The second aim was to explore the relationship between social cognition performances and executive abilities and mood variables. Methods: Sixty-two patients with MS and 33 healthy matched controls performed experimental tasks assessing facial emotion recognition, theory of mind (ToM), and cognitive functioning, in particular executive functions. Results: Patients differed from controls on both measures of social cognition. On the ToM measures, patients with progressive MS scored significantly lower than healthy participants. Patients with primary progressive MS performed worse than both healthy participants and patients with relapsing-remitting MS on the recognition of fearful facial expressions, while patients with secondary progressive MS performed worse on the recognition of facial expressions of sadness. Patients’ social cognition difficulties were correlated with processing speed, working memory, and verbal fluency. Conclusions: These preliminary results suggested that there may be qualitative differences in social cognition difficulties among the phenotypes. Furthermore, these impairments were related to executive functions, but unrelated to patients’ disability or level of depression. These data highlight the need for research to determine the real impact of these deficits on interpersonal relationships among patients and to confirm these disorders in a larger population with progressive forms of MS. (JINS, 2017, 23, 653–664)

Keywords

Theory of mindEmotion recognitionCognitionNeuropathologySocial skillsExecutive function
Type
Research Articles
Information
Journal of the International Neuropsychological Society , Volume 23 , Issue 8 , September 2017 , pp. 653 - 664
Copyright
Copyright © The International Neuropsychological Society 2017 

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