Hostname: page-component-cd9895bd7-jn8rn Total loading time: 0 Render date: 2024-12-29T08:41:57.889Z Has data issue: false hasContentIssue false
  • English
  • Français

New Yes/No Recognition Memory Analysis on the California Verbal Learning Test-3: Clinical Utility in Alzheimer’s and Huntington’s Disease

Published online by Cambridge University Press:  16 August 2018

Lisa V. Graves ,
Heather M. Holden ,
Emily J. Van Etten ,
Lisa Delano-Wood ,
Mark W. Bondi ,
David P. Salmon ,
Jody Corey-Bloom ,
Dean C. Delis  and
Paul E. Gilbert
Lisa V. Graves
Affiliation:
San Diego State University/University of California San Diego Joint Doctoral Program in Clinical Psychology, San Diego/La Jolla, California Department of Psychology, San Diego State University, San Diego, California
Heather M. Holden
Affiliation:
San Diego State University/University of California San Diego Joint Doctoral Program in Clinical Psychology, San Diego/La Jolla, California Department of Psychology, San Diego State University, San Diego, California
Emily J. Van Etten
Affiliation:
Department of Psychology, University of Arizona, Tucson, Arizona
Lisa Delano-Wood
Affiliation:
San Diego State University/University of California San Diego Joint Doctoral Program in Clinical Psychology, San Diego/La Jolla, California Veterans Affairs Healthcare System, San Diego, California Department of Psychiatry, University of California San Diego School of Medicine, La Jolla, California
Mark W. Bondi
Affiliation:
San Diego State University/University of California San Diego Joint Doctoral Program in Clinical Psychology, San Diego/La Jolla, California Veterans Affairs Healthcare System, San Diego, California Department of Psychiatry, University of California San Diego School of Medicine, La Jolla, California
David P. Salmon
Affiliation:
San Diego State University/University of California San Diego Joint Doctoral Program in Clinical Psychology, San Diego/La Jolla, California Department of Neurosciences, University of California San Diego, La Jolla, California
Jody Corey-Bloom
Affiliation:
San Diego State University/University of California San Diego Joint Doctoral Program in Clinical Psychology, San Diego/La Jolla, California Department of Neurosciences, University of California San Diego, La Jolla, California
Dean C. Delis
Affiliation:
San Diego State University/University of California San Diego Joint Doctoral Program in Clinical Psychology, San Diego/La Jolla, California Department of Psychiatry, University of California San Diego School of Medicine, La Jolla, California
Paul E. Gilbert*
Affiliation:
San Diego State University/University of California San Diego Joint Doctoral Program in Clinical Psychology, San Diego/La Jolla, California Department of Psychology, San Diego State University, San Diego, California
*
Correspondence and reprint requests to: Paul E. Gilbert, SDSU/UCSD Joint Doctoral Program in Clinical Psychology, 6363 Alvarado Court, Suite 103, San Diego, CA, 92120. E-mail: [email protected]
Get access Rights & Permissions [Opens in a new window]

Abstract

Objectives: The third edition of the California Verbal Learning Test (CVLT-3) includes a new index termed List A versus Novel/Unrelated recognition discriminability (RD) on the Yes/No Recognition trial. Whereas the Total RD index incorporates false positive (FP) errors associated with all distractors (including List B and semantically related items), the new List A versus Novel/Unrelated RD index incorporates only FP errors associated with novel, semantically unrelated distractors. Thus, in minimizing levels of source and semantic interference, the List A versus Novel/Unrelated RD index may yield purer assessments of yes/no recognition memory independent of vulnerability to source memory difficulties or semantic confusion, both of which are often seen in individuals with primarily frontal-system dysfunction (e.g., early Huntington’s disease [HD]). Methods: We compared the performance of individuals with Alzheimer’s disease (AD) and HD in mild and moderate stages of dementia on CVLT-3 indices of Total RD and List A versus Novel/Unrelated RD. Results: Although AD and HD subgroups exhibited deficits on both RD indices relative to healthy comparison groups, those with HD generally outperformed those with AD, and group differences were more robust on List A versus Novel/Unrelated RD than on Total RD. Conclusions: Our findings highlight the clinical utility of the new CVLT-3 List A versus Novel/Unrelated RD index, which (a) maximally assesses yes/no recognition memory independent of source and semantic interference; and (b) provides a greater differentiation between individuals whose memory disorder is primarily at the encoding/storage level (e.g., as in AD) versus at the retrieval level (e.g., as in early HD). (JINS, 2018, 24, 833–841)

Keywords

Alzheimer diseaseHuntington diseaseMemory disordersRecognitionMemory and learning testsNeuropsychological tests
Type
Regular Research
Information
Journal of the International Neuropsychological Society , Volume 24 , Issue 8 , September 2018 , pp. 833 - 841
Copyright
Copyright © The International Neuropsychological Society 2018 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

Alexander, G. E., Crutcher, M. D., & DeLong, M. R. (1990). Basal ganglia-thalamocortical circuits: Parallel substrates for motor, oculomotor, “prefrontal” and “limbic” functions. Progress in Brain Research, 85, 119–146.Google Scholar
Baldo, J. V., Delis, D., Kramer, J., & Shimamura, A. P. (2002). Memory performance on the California Verbal Learning Test-II: Findings from patients with focal frontal lesions. Journal of the International Neuropsychological Society, 8, 539–546.Google Scholar
Blumenfeld, R. S., & Ranganath, C. (2007). Prefrontal cortex and long-term memory encoding: An integrative review of findings from neuropsychology and neuroimaging. Neuroscientist, 13(3), 280–291.Google Scholar
Braak, H., & Braak, E. (1991). Neuropathological stageing of Alzheimer-related changes. Acta Neuropathologica, 82, 239–259.Google Scholar
Budson, A. E., & Kowall, N. W. (2013). Handbook of Alzheimer’s disease and other dementias. Hoboken, NJ: Wiley-Blackwell.Google Scholar
Butters, N., Wolfe, J., Granholm, E., & Martone, M. (1986). An assessment of verbal recall, recognition and fluency abilities in patients with Huntington’s disease. Cortex, 22, 11–32.Google Scholar
Butters, N., Wolfe, J., Martone, M., Granholm, E., & Cermak, L. S. (1985). Memory disorders associated with Huntington’s disease: Verbal recall, verbal recognition, and procedural memory. Neuropsychologia, 23, 729–743.Google Scholar
Crosson, B., Benefield, H., Cato, M. A., Sadek, J. R., Moore, A. B., Wierenga, C. E., & Briggs, R. W. (2003). Left and right basal ganglia and frontal activity during language generation: Contributions to lexical, semantic, and phonological processes. Journal of the International Neuropsychological Society, 9, 1061–1077.Google Scholar
Cummings, J. L. (1993). Frontal-subcortical circuits and human behavior. Archives of Neurology, 50, 873–880.Google Scholar
Delis, D. C., Kramer, J. H., Kaplan, E., & Ober, B. A. (1987). California Verbal Learning Test. San Antonio, TX: The Psychological Corporation.Google Scholar
Delis, D. C., Kramer, J. H., Kaplan, E., & Ober, B. A. (2000). California Verbal Learning Test–II (Second Edition, San Antonio, TX: The Psychological Corporation.Google Scholar
Delis, D. C., Kramer, J. H., Kaplan, E., & Ober, B. A. (2017). California Verbal Learning Test–3 (Third Edition, San Antonio, TX: The Psychological Corporation.Google Scholar
Delis, D. C., Massman, P. J., Butters, N., Salmon, D. P., Cermak, L. S., & Kramer, J. H. (1991). Profiles of demented and amnesic patients on the California Verbal Learning Test: Implications for the assessment of memory disorders. Psychological Assessment, 3, 19–26.Google Scholar
Delis, D. C., Wetter, S. R., Jacobson, M. W., Peavy, G., Hamilton, J., Gongvatana, A., & Salmon, D. P. (2005). Recall discriminability: Utility of a new CVLT-II measure in the differential diagnosis of dementia. Journal of the International Neuropsychological Society, 11(6), 708–715.Google Scholar
Fine, E. M., Delis, D. C., Wetter, S. R., Jacobson, M. W., Hamilton, J. M., Peavy, G., & Salmon, D. P. (2008). Identifying the “source” of recognition memory deficits in patients with Huntington’s disease or Alzheimer’s disease: Evidence from the CVLT-II. Journal of Clinical and Experimental Neuropsychology, 30(4), 463–470.Google Scholar
Graves, L. V., Holden, H. M., Woods, S. P., Delano-Wood, L., Bondi, M., Salmon, D. P., & Gilbert, P. E. (2017). Total recognition discriminability in Huntington’s and Alzheimer’s disease. Journal of Clinical and Experimental Neuropsychology, 39(2), 120–130.Google Scholar
Hodges, J. R., Salmon, D. P., & Butters, N. (1990). Differential impairment of semantic and episodic memory in Alzheimer’s and Huntington’s diseases: A controlled prospective study. Journal of Neurology, Neurosurgery, and Psychiatry, 53(12), 1089–1095.Google Scholar
Huntington Study Group. (1996). Unified Huntington’s disease rating scale: Reliability and consistency. Movement Disorders, 11, 136–142.Google Scholar
Hyman, B. T., Van Hoesen, G. W., Damasio, A. R., & Barnes, C. L. (1984). Alzheimer’s disease: Cell-specific pathology isolates the hippocampal formation. Science, 225, 1168–1170.Google Scholar
Jurica, P. J., Leitten, S., & Mattis, S. (2001). Dementia Rating Scale-2: Professional manual. Lutz, FL: Psychological Assessment Resources.Google Scholar
Kramer, J. H., Delis, D. C., Blusewicz, M. J., Brandt, J., Ober, B. A., & Strauss, M. (1988). Verbal memory errors in Alzheimer’s and Huntington’s dementias. Developmental Neuropsychology, 4, 1–15.Google Scholar
Kramer, J. H., Levin, B. E., Brandt, J., & Delis, D. C. (1989). Differentiation of Alzheimer’s, Huntington’s, and Parkinson’s disease patients on the basis of verbal learning characteristics. Neurology, 3, 111–120.Google Scholar
Lundervold, A. J., Reinvang, I., & Lundervold, A. (1994). Characteristic patterns of verbal memory function in patients with Huntington’s disease. Scandinavian Journal of Psychology, 35(1), 38–47.Google Scholar
Macmillan, N. A., & Creelman, D. C. (1991). Detection theory: A user’s guide. New York: Cambridge University Press.Google Scholar
Martone, M., Butters, N., Payne, M., Becker, J. T., & Sax, D. S. (1984). Dissociations between skill learning and verbal recognition in amnesia and dementia. Archives of Neurology, 41, 965–970.Google Scholar
Massman, P. J., Delis, D. C., Butters, N., Levin, B. E., & Salmon, D. P. (1990). Are all subcortical dementias alike? Verbal learning and memory in Parkinson’s and Huntington’s disease patients. Journal of Clinical and Experimental Neuropsychology, 12(5), 729–744.Google Scholar
McKhann, G., Drachman, D., Folstein, M., Katzman, R., Price, D., & Stadlan, E. M. (1984). Clinical diagnosis of Alzheimer’s disease: Report of the NINCDS–ADRDA work group under the auspices of the Department of Health and Human Services Task Force on Alzheimer’s disease. Neurology, 34, 939–944.Google Scholar
McKhann, G. M., Knopman, D. S., Chertkow, H., Hyman, B. T., Jack, C. R. Jr., Kawas, C. H., & Phelps, C. H. (2011). The diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute on Aging and the Alzheimer’s Association workgroup. Alzheimer’s & Dementia, 7(3), 263–269.Google Scholar
Montoya, A., Pelletier, M., Menear, M., Duplessis, E., Richer, F., & Lepage, M. (2006). Episodic memory impairment in Huntington’s disease: A meta-analysis. Neuropsychologia, 44, 1984–1994.Google Scholar
Moss, M. B., Albert, M. S., Butters, N., & Payne, M. (1986). Differential patterns of memory loss among patients with Alzheimer’s disease, Huntington’s disease, and alcoholic Korsakoff’s syndrome. Archives of Neurology, 43, 239–246.Google Scholar
Salmon, D. P., & Bondi, M. W. (2009). Neuropsychological assessment of dementia. Annual Review of Psychology, 60, 257–282.Google Scholar
Salmon, D. P., & Filoteo, J. V. (2007). Neuropsychology of cortical versus subcortical dementia syndromes. Seminars in Neurology, 27, 7–21.Google Scholar
Troster, A. I., Butters, N., Salmon, D. P., Cullum, C. M., Jacobs, D., Brandt, J., & White, R. R. (1993). The diagnostic utility of savings scores: Differentiating Alzheimer’s and Huntington’s diseases with the logical memory and visual reproduction tests. Journal of Clinical and Experimental Neuropsychology, 15, 773–788.Google Scholar
Tulving, E., Kapur, S., Craik, F. I., Moscovitch, M., & Houle, S. (1994). Hemispheric encoding/retrieval asymmetry in episodic memory: Positron emission tomography findings. Proceedings of the National Academy of Sciences of the United States of America, 91, 2016–2020.Google Scholar
Vonsattel, J. P. (2000). Neuropathology of Huntington’s disease. NeuroScience News, 3, 45–53.Google Scholar
Vonsattel, J., Myers, R., Stevens, T. J., Ferrante, R. J., Bird, E. D., & Richardson, E. P. (1985). Neuropathological classification of Huntington’s disease. Journal of Neuropathology and Experimental Neurology, 44, 559–577.Google Scholar