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Second primary tumour following retinoblastoma

Published online by Cambridge University Press:  29 June 2007

D. C. Berridge ,
A. Hitchcock ,
P. J. Bradley  and
L. Kapila
D. C. Berridge*
Affiliation:
Department of Paediatric Surgery, University Hospital, Queen's Medical Centre, Nottingham NG7 2UH
A. Hitchcock
Affiliation:
Histopathology, University Hospital, Queen's Medical Centre, Nottingham NG7 2UH
P. J. Bradley
Affiliation:
Otolarngology/Head and Neck Oncology, University Hospital, Queen's Medical Centre, Nottingham NG7 2UH
L. Kapila
Affiliation:
Department of Paediatric Surgery, University Hospital, Queen's Medical Centre, Nottingham NG7 2UH
*
Mr. D. C. Berridge, Department of Paediatric Surgery, E Floor, East Block, University Hospital, Queen's Medical Centre, Nottingham. NG7 2UH
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Abstract

Reported is a child who at the age of 18 months had presented with a left retinoblastoma. The lesion had involved the optic nerve (Stage IV), and was successfully treated by enucleation and radiotherapy. The radiation field did not include the mandible or the submandibular triangle. He was followed up until he left the area aged 11 years. He represented aged 12 years with a progressive swelling of the left submandibular gland. Histology of the surgically excised submandibular gland revealed a mucoepidermoid carcinoma of the submandibular gland. This case highlights the need for continual surveillance in survivors of retinoblastoma, as second primary tumours occur both within and outside of previous radiation fields. The clinical association between retinoblastoma and mucoepidermoid carcinoma of the submandibular gland has not been previously reported.

Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 103 , Issue 7 , July 1989 , pp. 690 - 691
Copyright
Copyright © JLO (1984) Limited 1989

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References

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