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Is there an association between blood group O and epistaxis?

Published online by Cambridge University Press:  08 March 2017

V M Reddy ,
M Daniel ,
E Bright ,
S R Broad  and
A A Moir
V M Reddy*
Affiliation:
Department of Otorhinolaryngology, Leicester Royal Infirmary, Leicester, UK
M Daniel
Affiliation:
Department of Otorhinolaryngology, Leicester Royal Infirmary, Leicester, UK
E Bright
Affiliation:
Department of Otorhinolaryngology, Leicester Royal Infirmary, Leicester, UK
S R Broad
Affiliation:
Department of Otorhinolaryngology, Leicester Royal Infirmary, Leicester, UK
A A Moir
Affiliation:
Department of Otorhinolaryngology, Leicester Royal Infirmary, Leicester, UK
*
Address for correspondence: Mr V M Reddy, 226 Avenue Road Extension, Leicester, LE2 3EL, UK. Fax: 0870 123 6196 E-mail: [email protected]
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Abstract

Introduction:

Blood group O is associated with lower expression of von Willebrand factor suggesting a relative bleeding tendency. A lower admission rate for epistaxis among Asians compared with Caucasians has also been noted, with one explanation being higher prevalence of blood group O among Caucasians. This study investigates whether blood group O is over-represented in patients admitted with epistaxis.

Methods:

A retrospective study was conducted, using computerised hospital in-patient and blood bank databases to identify Caucasians admitted with epistaxis between January 2000 and December 2005 inclusive. The control group consisted of 500 consecutive patients who had a primary total hip arthroplasty and 500 consecutive patients who gave birth within the delivery suite.

Results:

1261 Caucasians admitted with epistaxis were identified. Among epistaxis patients, 50.44 per cent were blood group O but among the control group this was 45.10 per cent (chi-square test p = 0.008).

Conclusion:

Blood group O appears over-represented in Caucasian patients admitted with epistaxis, compared with the control population, raising the possibility that blood group O is a risk factor for epistaxis.

Keywords

EpistaxisABO Blood-Group SystemVon Willebrand FactorFactor IX
Type
Main Article
Information
The Journal of Laryngology & Otology , Volume 122 , Issue 4 , April 2008 , pp. 366 - 368
Copyright
Copyright © JLO (1984) Limited 2007

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Footnotes

Abstract presented at the Otorhinolaryngological Research Society Autumn Meeting, 29 September 2006, Institute of Laryngology and Otology, London, UK.

References

1 Pallin, DJ, Chng, YM, McKay, MP, Emond, JA, Pelletier, AJ, Camargo, CA Jr. Epidemiology of epistaxis in US emergency departments, 1992 to 2001. Ann Emerg Med 2005;46:77–81CrossRefGoogle ScholarPubMed
2 Daniel, M, Jaberoo, MC, Stead, RE, Reddy, VM, Moir, AA. Is admission for epistaxis more common in Caucasian than in Asian people? A preliminary study. Clin Otolaryngol 2006;31:386–9CrossRefGoogle ScholarPubMed
3 Mourant, AE. Blood relations: Blood groups and anthropology. Oxford: Oxford University Press, 1983Google Scholar
4 Favaloro, EJ, Soltani, S, McDonald, J, Grezchnik, E, Easton, L, Favaloro, JW. Reassessment of ABO blood group, sex, and age on laboratory parameters used to diagnose von Willebrand disorder: potential influence on the diagnosis vs the potential association with risk of thrombosis. Am J Clin Pathol 2005;124:910–17CrossRefGoogle ScholarPubMed
5 Gill, JC, Endres-Brooks, J, Bauer, PJ, Marks, WJ Jr, Montgomery, RR. The effect of ABO blood group on the diagnosis of von Willebrand disease. Blood 1987;69:1691–5CrossRefGoogle ScholarPubMed
6 Miller, CH, Haff, E, Platt, SJ, Rawlins, P, Drews, CD, Dilley, AB et al. Measurement of von Willebrand factor activity: relative effects of ABO blood type and race. J Thromb Haemost 2003;1:2191–7CrossRefGoogle ScholarPubMed
7 Caekebeke-Peerlinck, KM, Koster, T, Briet, E. Bleeding time, blood groups and von Willebrand factor. Br J Haematol 1989;73:217–20CrossRefGoogle ScholarPubMed
8 Koster, T, Blann, AD, Briet, E, Vandenbroucke, JP, Rosendaal, FR. Role of clotting factor VIII in effect of von Willebrand factor on occurrence of deep-vein thrombosis. Lancet 1995;345:152–5CrossRefGoogle ScholarPubMed
9 Halonen, P, Linko, K, Wirtavuori, K, Hastbacka, J, Ikkala, E. Evaluation of risk factors in intraoperative bleeding tendency. Ann Chir Gynaecol 1987;76:298–302Google ScholarPubMed