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Effects of passive smoking on adult nasal respiratory mucosa

Published online by Cambridge University Press:  08 October 2013

S Elwany*
Affiliation:
Department of Otolaryngology, Alexandria Medical School, Egypt
Y H Saeed
Affiliation:
Department of Otolaryngology, Alexandria Medical School, Egypt
I Talaat
Affiliation:
Department of Pathology, Alexandria Medical School, Egypt
*
Address for correspondence: Dr Samy Elwany, 4 Kfr Abdou St # 605, Alexandria, Egypt E-mail: [email protected]

Abstract

Objective:

The present study aimed to investigate nasal mucosal changes in response to passive exposure to cigarette smoke.

Study design:

The study included 20 women aged 35–51 years who were scheduled for non-rhinological surgical procedures, and who had at least 10 years' prolonged passive exposure to household cigarette smoke. During surgery, two 1-mm3 biopsies of nasal mucosa were taken from the lower border of the inferior turbinate. Specimens were processed and examined with light and transmission electron microscopy.

Results:

Examination of the nasal mucosa showed several histopathological changes. The severity of structural changes increased with duration of smoke exposure. No allergic or neoplastic changes were seen.

Conclusion:

Passive exposure to cigarette smoke has a deleterious effect on the nasal respiratory mucosa. Prolonged passive smoke exposure may also induce other, significant changes not detected in the present study.

Type
Main Articles
Copyright
Copyright © JLO (1984) Limited 2013 

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References

1Pell, JP, Haw, S, Cobbe, S. Smoke-free legislation and hospitalizations for acute coronary syndrome. N Engl J Med 2008;359:482–91CrossRefGoogle ScholarPubMed
2Dessi, P, Sambuc, R, Movlin, G, Iedoray, V. Effect of heavy smoking on nasal resistance. Acta Otolaryngol (Stockh) 1994;114:305–10CrossRefGoogle ScholarPubMed
3Gedikondele, JS, Longo-Mbenza, B, Nzanza, JM, Luila, EL, Reddy, P, Buso, D. Nose and throat complications associated with passive smoking among Congolese school children. Afr Health Sci 2011;11:315–9Google ScholarPubMed
4Stanković, A, Nikolić, M, Arandelović, M. Exposure to environmental tobacco smoke and absence from work in women in Nis, Serbia. Cent Eur J Public Health 2012;20:24–8CrossRefGoogle ScholarPubMed
5Vinke, J, Denjan, A, Severijnen, L, Fottens, J. Passive smoking causes an ‘allergic’ cell infiltrate in the nasal mucosa of non-atopic children. Int J Pediatr Otolaryngol 1999;51:7381CrossRefGoogle ScholarPubMed
6Nageris, B, Hadar, T, Hansen, M. The effect of passive smoking on olfaction in children. Rev Laryngol Otol Rhinol (Bord) 2002;128:8991Google Scholar
7Usenius, T, Karja, J, Collan, Y. Squamous cell carcinoma of the tongue in children. Cancer 1987;60: 236–93.0.CO;2-W>CrossRefGoogle ScholarPubMed
8Samet, JM. Secondhand smoke: facts and lies. Salud Publica Mex 2008;50:428–34CrossRefGoogle ScholarPubMed
9Atef, A, Abo Zeid, I, Qotb, M, Gad El Rab, E. Effect of passive smoking on ciliary regeneration of nasal mucosa after functional endoscopic sinus surgery in children. J Laryngol Otol 2009;123:75–9CrossRefGoogle ScholarPubMed
10Torjussen, W, Solberg, LA, Hogeveit, A. Histopathological changes of the nasal mucosa in nickel workers. Cancer 1979;44:693–743.0.CO;2-H>CrossRefGoogle ScholarPubMed
11Agius, A, Smallman, L, Pahor, A. Age, smoking and ciliary beat frequency. Clin Otolaryngol 1998;23:227–30CrossRefGoogle ScholarPubMed
12Rogers, DF, Jeffery, PK. Inhibition of cigarette smoke induced airway secretory cell hyperplasia by indomethacin, dexamethasone, prednisolone, or hydrocortisone in the rat. Exp Lung Res 1986;10:285–98CrossRefGoogle ScholarPubMed
13Jeffery, PK. The effect of tobacco smoke, with and without phenylmethyloxadiazole (PMO) on rat bronchial epithelium: a light and electron microscopic study. J Pathol 1981;133:341–59CrossRefGoogle ScholarPubMed
14Toppozada, H, Talaat, M. Human nasal epithelium and cellular elements in chronic allergic rhinitis. ORL J Otorhinolaryngol Relat Spec 1975;37:333–43CrossRefGoogle ScholarPubMed
15Toppozada, H, Talaat, M. Tunica propria in chronic allergic rhinitis. Electron-microscopic study II. The sero-mucinous glands. ORL J Otorhinolaryngol Relat Spec 1976;38:8698CrossRefGoogle ScholarPubMed
16Elwany, S, Bumsted, R. Ultrastructural observations on vasomotor rhinitis. ORL J Otorhinolaryngol Relat Spec 1987;49:199205CrossRefGoogle ScholarPubMed
17Dye, JA, Adler, KB. Effects of cigarette smoke on epithelial cells of the respiratory tract. Thorax 1994;49:825–34CrossRefGoogle ScholarPubMed
18Benninger, MS. The impact of cigarette smoking and environmental tobacco smoke on nasal sinus disease: a review of the literature. Am J Rhinol 1999;13:435–8CrossRefGoogle ScholarPubMed