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Are the morphology of papillary thyroid carcinoma and the tumour's behaviour correlated?

Published online by Cambridge University Press:  29 June 2007

Tsila Hefer*
Affiliation:
Departments of Otolaryngology, Rambam, Medical Center, Faculty of Medicine, Technion, Haifa, Israel
Henry Z. Joachims
Affiliation:
Departments of Otolaryngology, Rambam, Medical Center, Faculty of Medicine, Technion, Haifa, Israel
Arie Eitan
Affiliation:
Departments of Surgery A, Rambam, Medical Center, Faculty of Medicine, Technion, Haifa, Israel
Mariana Munichor
Affiliation:
Departments of Pathology, Rambam, Medical Center, Faculty of Medicine, Technion, Haifa, Israel
*
Address for correspondence: Dr Tsila Hefer, M.D., Department of Otorhinolaryngology, Rambam Medical Center, Haifa, Israel.

Abstract

Six cases of papillary thyroid carcinoma showing clinically highly aggressive behaviour by invading the upper airway and digestive tract structures were retrospectively reviewed to evaluate the morphological variants of the tumours. Four of them were found to be pure papillary and one was a mixed-papillary and follicular-variants regarded as non-aggressive. Only one case was found to be tall cell variant – regarded as an aggressive variant of papillary thyroid carcinoma. The findings suggest that the prognosis of papillary thyroid carcinoma cannot be predicted from its morphological variant and attention should be given to other clinical parameters.

Type
Pathology in Focus
Copyright
Copyright © JLO (1984) Limited 1996

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