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Young systemic lupus erythematosus patients with no hearing involvement: 10-year follow up

Published online by Cambridge University Press:  07 December 2012

J R García-Berrocal ,
B De Diego ,
A Roldán-Fidalgo ,
M Yebra-Bango ,
I Millán ,
A Trinidad  and
R Ramírez-Camacho
J R García-Berrocal
Affiliation:
Department of Otorhinolaryngology, Hospital Universitario Puerta de Hierro-Majadahonda, Madrid, Spain Faculty of Medicine, Universidad Autónoma de Madrid, Spain Department of Statistics, Hospital Universitario Puerta de Hierro-Majadahonda, Madrid, Spain
B De Diego*
Affiliation:
Department of Otorhinolaryngology, Hospital Universitario Puerta de Hierro-Majadahonda, Madrid, Spain Faculty of Medicine, Universidad Autónoma de Madrid, Spain Department of Statistics, Hospital Universitario Puerta de Hierro-Majadahonda, Madrid, Spain
A Roldán-Fidalgo
Affiliation:
Department of Otorhinolaryngology, Hospital Universitario Puerta de Hierro-Majadahonda, Madrid, Spain Faculty of Medicine, Universidad Autónoma de Madrid, Spain Department of Statistics, Hospital Universitario Puerta de Hierro-Majadahonda, Madrid, Spain
M Yebra-Bango
Affiliation:
Faculty of Medicine, Universidad Autónoma de Madrid, Spain Department of Internal Medicine, Hospital Universitario Puerta de Hierro-Majadahonda, Madrid, Spain Department of Statistics, Hospital Universitario Puerta de Hierro-Majadahonda, Madrid, Spain
I Millán
Affiliation:
Faculty of Medicine, Universidad Autónoma de Madrid, Spain Department of Statistics, Hospital Universitario Puerta de Hierro-Majadahonda, Madrid, Spain
A Trinidad
Affiliation:
Department of Otorhinolaryngology, Hospital Universitario Puerta de Hierro-Majadahonda, Madrid, Spain Faculty of Medicine, Universidad Autónoma de Madrid, Spain Department of Statistics, Hospital Universitario Puerta de Hierro-Majadahonda, Madrid, Spain
R Ramírez-Camacho
Affiliation:
Department of Otorhinolaryngology, Hospital Universitario Puerta de Hierro-Majadahonda, Madrid, Spain Faculty of Medicine, Universidad Autónoma de Madrid, Spain Department of Statistics, Hospital Universitario Puerta de Hierro-Majadahonda, Madrid, Spain
*
Address for correspondence: Dr Beatriz De Diego, Department of Otorhinolaryngology, Hospital Universitario Puerta de Hierro-Majadahonda, Manuel de Falla 1, 28222 Majadahonda, Madrid, Spain Fax: +34 913730535 E-mail: [email protected]
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Abstract

Objective:

To evaluate patients with systemic lupus erythematosus and normal hearing over 10 years, compared with healthy controls.

Methods:

Thirty patients diagnosed with systemic lupus erythematosus were evaluated in a prospective, descriptive study. Eight patients fulfilled the inclusion criteria, i.e. normal otoscopy, normal hearing, normal imaging and disease duration of less than one year. Eleven healthy companions of ENT patients were recruited as controls.

Results:

At study commencement, the mean patient age was 32.75 years (range, 15–49 years) and there were no statistically significant audiometric differences between patients and controls. No statistically significant audiometric changes were found either within or between the patient and control groups at 10-year follow up.

Conclusion:

These results supply no evidence for progressive hearing loss in systemic lupus erythematosus patients with no hearing involvement at study commencement. Therefore, we recommend audiometric tests only for systemic lupus erythematosus patients complaining of hearing loss, or for other clinical purposes. It is conceivable that asymptomatic hearing loss could be observed over a more extended follow-up period (i.e. more than 10 years).

Keywords

Hearing LossLupus ErythematosusSystemicAntibodiesAnticardiolipinAntibodiesAntiphospholipid
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 127 , Issue 1 , January 2013 , pp. 38 - 42
Copyright
Copyright © JLO (1984) Limited 2012

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References

1 Bowman, CA, Linthicum, FH, Nelson, RA, Mikami, M, Quismorio, F. Sensorineural hearing loss associated with systemic lupus erythematosus. Otolaryngol Head Neck Surg 1986;94:197–204 Google Scholar
2 Caldarelli, DD, Rejowski, JE, Corey, JP. Sensorineural hearing loss in lupus erythematosus. Am J Otolaryngol 1986;7:210–13Google Scholar
3 Khalidi, NA, Rebello, R, Robertson, DD. Sensorineural hearing loss in systemic lupus erythematosus: case report and review of literature. J Laryngol Otol 2008;122:1371–6CrossRefGoogle Scholar
4 Roverano, S, Cassano, G, Paira, S, Chiavarini, J, Graf, C, Rico, L et al. Asymptomatic sensorineural hearing loss in patients with systemic lupus erythematosus. J Clin Rheumatol 2006;12:217–20CrossRefGoogle ScholarPubMed
5 Karatas, E, Onat, AM, Durucu, C, Baglam, T, Kanlikama, M, Altunoren, O et al. Audiovestibular disturbance in systemic lupus erythematosus. Otolaryngol Head Neck Surg 2007;136:82–6Google Scholar
6 Hisashi, K, Komune, S, Taira, T, Uemura, T, Sadoshima, S, Tsuda, H. Anticardiolipin antibody induced sudden profound sensorineural hearing loss. Am J Otolaryngol 1993;14:275–7CrossRefGoogle ScholarPubMed
7 Compadretti, GC, Brandolini, C, Tasca, I. Sudden sensorineural hearing loss in lupus erythematosus associated with antiphospholipid syndrome: case report and review. Ann Otol Laryngol 2005;114:214–18CrossRefGoogle ScholarPubMed
8 Tan, E, Cohen, A, Fries, JF, Masi, AT, McShane, DJ, Rothfield, NF et al. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 1982;25:1271–7CrossRefGoogle ScholarPubMed
9 McCabe, BF. Autoimmune sensorineural hearing loss. Ann Otol Rhinol Laryngol 1979;88:585–9Google Scholar
10 García-Berrocal, JR, Vargas, JA, Vaquero, M, Ramón y Cajal, S, Ramírez-Camacho, R. Cogan's syndrome: an oculo-audiovestibular disease. Postgrad Med J 1999;75:262–4CrossRefGoogle ScholarPubMed
11 García-Berrocal, JR, Ramírez-Camacho, R, Millán, I, Górriz, C, Arellano, B, Trinidad, A et al. Sudden presentation of immune-mediated inner ear disease: characterization and acceptance of a cochleovestibular dysfunction. J Laryngol Otol 2003;117:775–9CrossRefGoogle ScholarPubMed
12 García-Berrocal, JR, Ramírez-Camacho, R. Sudden sensorineural hearing loss: supporting the immunologic theory. Ann Otol Rhinol Laryngol 2002;111:989–97CrossRefGoogle Scholar
13 Andonopoulos, AP, Naxakis, S, Goumas, P, Lygatsikas, C. Sensorineural hearing disorders in systemic lupus erythematosus. A controlled study. Clin Exp Rheumatol 1995;13:137–41Google Scholar
14 Sone, M, Schachern, PA, Paparella, MM, Morizono, N. Study of systemic lupus erythematosus in temporal bones. Ann Otol Rhinol Laryngol 1999;108:338–44Google Scholar
15 Karabulut, H, Dagli, M, Ates, A, Karaaslan, Y. Results for audiology and distortion product and transient evoked otoacoustic emissions in patients with systemic lupus erythematosus. J Laryngol Otol 2010;124:137–40Google Scholar
16 Cordeschi, S, Salvinelli, F, D'Ascanio, L. Sensorineural impairment in systemic lupus erythematosus: sudden or progressive? Clin Exp Rheumatol 2004;22:653Google ScholarPubMed
17 Gomides, AP, do Rosário, EJ, Borges, HM, Gomides, HHM, de Pádua, PM, Sampaio-Barros, PD. Sensorineural dysacusis in patients with systemic lupus erythematosus. Lupus 2007;16:987–90Google Scholar
18 Maciaszczyk, K, Durko, T, Waszczykowska, E, Erkiert-Polguj, A, Pajor, A. Auditory function in patients with systemic lupus erythematosus. Auris Nasus Larynx. 2011;38:26–32 Google Scholar
19 Bouman, H, Klis, SF, de Groot, JC, Huizing, EH, Smoorenburg, GF, Veldman, JE. Induction of endolymphatic hydrops in the guinea pig by perisaccular deposition of sepharose beads carrying and not carrying immune complexes. Hear Res 1998;117:119–30Google Scholar
20 Seckin, U, Ozoran, K, Kinciogullari, A, Borman, P, Bostan, EE. Hydroxycholoroquine ototoxicity in a patient with rheumatoid arthritis. Rheumatol Int 2000;19:203–4Google Scholar
21 Kastanioudakis, I, Ziavra, N, Voulgari, PV, Exarchakos, G, Skevas, A, Drosos, AA. Ear involvement in systemic lupus erythematosus patients: a comparative study. J Laryngol Otol 2002;116:103–7CrossRefGoogle ScholarPubMed