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Serum leucine aminopeptidase in head and neck cancer

Published online by Cambridge University Press:  29 June 2007

L. N. Garg ,
S. P. S. Yadav  and
Harbans Lal
L. N. Garg
Affiliation:
Departments of Otolaryngology, Medical College and Hospital, Rohtak-124001, India
S. P. S. Yadav
Affiliation:
Departments of Otolaryngology, Medical College and Hospital, Rohtak-124001, India
Harbans Lal*
Affiliation:
Departments of Biochemistry, Medical College and Hospital, Rohtak-124001, India
*
Dr Harbans Lal, Associate Professor Biochemistry, 15/8FM, Medical College, Rohtak-124001, India..
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Abstract

Serum leucine aminopeptidase (LAP) activity was assayed in patients with head and neck cancer. The levels were found to be significantly higher than the controls. However, the rise in serum LAP was nearly the same in all the patients studied, irrespective of the character or histopathology of the lesion but varied with respect to the site involved, i.e. from about 40 per cent in cancer of the hypopharynx to more than 100 per cent in cancer of the nasopharynx. Serum LAP activity was found to increase with the extent of the lymph node spread. After treatment the levels were found to be reduced.

Keywords

Leucine aminopeptidaseNeoplasm stagingNeoplasm metastasisLymph nodesHead and neck neoplasms
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 108 , Issue 8 , August 1994 , pp. 660 - 662
Copyright
Copyright © JLO (1984) Limited 1994

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