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Bilateral axillary metastasis from a primary ethmoidal squamous cell carcinoma

Published online by Cambridge University Press:  22 March 2006

S Islam ,
C V Cole ,
G R Hoffman  and
P A Brennan
S Islam
Affiliation:
University Hospitals of Coventry & Warwickshire NHS Trust, Coventry, UK
C V Cole
Affiliation:
University Hospitals of Coventry & Warwickshire NHS Trust, Coventry, UK
G R Hoffman
Affiliation:
University Hospitals of Coventry & Warwickshire NHS Trust, Coventry, UK
P A Brennan
Affiliation:
University Hospitals of Coventry & Warwickshire NHS Trust, Coventry, UK
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Abstract

The development of infra-clavicular lymph node metastasis from head and neck squamous cell carcinoma is an uncommon event. We present a rare case of bilateral axillary nodal metastasis that developed in a patient previously treated for a primary ethmoidal squamous cell carcinoma. To our knowledge, there have only been five case reports in the English literature, accounting for a total of 10 patients, which documented a clinically apparent metastasis to axillary lymph nodes from various head and neck malignancies. Significantly however, the simultaneous ipsilateral and contralateral lymphatic spread of disease from a tumour in the para-nasal sinus, so as to involve bi-axillary nodes, has not been previously reported. We discuss the possible pathogenesis and the prognostic significance of this manifestation.

Keywords

Neoplasm MetastasisHead And Neck NeoplasmsAxillaEthmoid SinusCarcinoma, Squamous
Type
Clinical Record
Information
The Journal of Laryngology & Otology , Volume 120 , Issue 4 , April 2006 , pp. 353 - 355
Copyright
2006 JLO (1984) Limited

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