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The site selected by the larvae of Heligmosomoides polygyrus

Published online by Cambridge University Press:  18 November 2009

M. V. K. Sukhdeo
Affiliation:
Institute of Parasitology, McGill University, Macdonald College, Ste. Anne de Bellevue, Quebec, H9X ICO Canada
R. T. O'Grady
Affiliation:
Institute of Parasitology, McGill University, Macdonald College, Ste. Anne de Bellevue, Quebec, H9X ICO Canada
S. C. Hsu
Affiliation:
Institute of Parasitology, McGill University, Macdonald College, Ste. Anne de Bellevue, Quebec, H9X ICO Canada

Abstract

Histological examination of the small intestine of mice infected with Heligmosomoides polygyrus indicates that the final site of the larvae is in the circular muscle layer of the muscularis externa of the anterior small intestine. The larvae become embedded in the muscle between the first and third days after infection and are subsequently sequestered by a localized leucocytic response. There is no evidence of a true cyst. Histological evidence suggests that the larvae actively feed on the tissues of the host during their development.

Type
Research Note
Copyright
Copyright © Cambridge University Press 1984

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