Hostname: page-component-586b7cd67f-t7czq Total loading time: 0 Render date: 2024-11-24T05:58:01.175Z Has data issue: false hasContentIssue false
  • English
  • Français

Transplantation of Adult Dirofilaria roemeri to Grey Kangaroos and Laboratory Rats*

Published online by Cambridge University Press:  05 June 2009

David M. Spratt
David M. Spratt
Affiliation:
Department of Parasitology, University of Queensland, St. Lucia, Brisbane 4067, Queensland, Australia
Get access Rights & Permissions [Opens in a new window]

Extract

Adult Dirofilaria roemeri were transplanted subcutaneously into two grey kangaroos and intraperitoneally into seven laboratory rats in an investigation of amicrofilaraemia, and for experimental transmission studies. Low level blood microfilaraemias of only short duration were produced in all but one rat, supporting the hypothesis that the grey kangaroo is an abnormal host of this parasite. Cortisone was instrumental in the success of D. roemeri in rats. Peritoneal lavage of rats harbouring transplanted D. roemeri proved an excellent source of microfilariae. Injection of large numbers of microfilariae into the saphenous veins of rats harbouring transplanted worms failed to alter the number of circulating microfilariae. D. roemeri failed to develop in Aedes aegypti, fed on rats harbouring transplanted worms and exhibiting blood microfilaraemia. One kangaroo, to which worms had been transplanted, was exposed to the bites of Dasybasis hebes (Diptera, Tabanidae) in the study area and acquired a natural infection of D. roemeri.

Type
Research Article
Information
Journal of Helminthology , Volume 46 , Issue 1 , March 1972 , pp. 81 - 89
Copyright
Copyright © Cambridge University Press 1972

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

Anderson, R. C., 1956.—“The life-cycle and seasonal transmission of Ornitho-filaria fallisensis Anderson, a parasite of domestic and wild ducks”. Can. J. Zool., 34, 485–525.CrossRefGoogle Scholar
Ansari, J. A., 1964.—“Studies on Setarta cervi (Nematoda : Filarioidea). Part II. Its peritoneal transplant and periodicity of the microfilariae in white rats”. Z. ParasitKde, 24, 105–111.Google Scholar
Bezubik, B. and Furmaga, S., 1904.—“Some observations on Setarta equina Abildgaard, 1789”. Acta parasit. pol., 12, 1–5.Google Scholar
Briggs, N. T., 1959.—“The effect of cortisone on natural resistance and acquired responses of the white rat to infection with Litomosoides carinii”. J. Parasit., 45 (Supp. 1), 37.Google Scholar
Frank, W., 1964.—“Die Entwicklung von Macdonaldius oschei Chabaud et Frank, 1961 (Filarioidea: Onchocercidae) in der Lederzecke Ornitho- doros talaje Guerin-Meneville (Ixodoidea, Argasidae)”. Z. ParasitenKde, 24, 319–350.Google Scholar
Furmaga, S., 1964.—“Observations on Setaria cervi (Rudolphi, 1819)”. Acta parasit. pol., 12, 7–12.Google Scholar
Gooneratne, B. W. M., 1968.—“On a successful peritoneal transplant of Cardiofilaria nilesi into an experimental chicken”. J. Helminth., 42, 279–282.CrossRefGoogle ScholarPubMed
Gooneratne, B. W. M., 1969.—“On Cardiofilaria nilesi in experimentally infected chickens with a note on the morphology and periodicity of the microfilariae”. J. Helminth., 43, 311–317.CrossRefGoogle ScholarPubMed
Nelson, G. S., 1962.—“Observations on the development of Setaria labiato- papillosa using new techniques for infecting Aedes aegypti with this nematode”. J. Helminth., 36, 281–290.CrossRefGoogle Scholar
Nelson, G. S., 1964.—“Factors influencing the development and behaviour of filarial nematodes in their arthropod hosts”, pp. 75–119. In Taylor, A.E.R. (ed.), “Host-parasite relationships in invertebrate hosts”. Second Symposium, Brit. Soc. Parasit. Blackwell, Oxford.Google Scholar
Olson, L. J., 1959.—“The cellular response of white rats to Litomosoides carinii larvae as influenced by cortisone, age, and previous infection”. J. Parasit., 45, 519–532.CrossRefGoogle ScholarPubMed
Parker, J. C., 1961.—“Effect of cortisone on the resistance of the guinea pig to infection with the rat nematode Nipposirongylus braziliensis”. Expl. Parasit., 11, 380–390.CrossRefGoogle Scholar
Ramakrishnan, S. P., Singh, D. and Krishnaswami, A. K., 1962.—“Evidence of acquired immunity against microfilariae of Litomosoides carinii in albino rats with mite-induced infection”. Indian J. Malar., 16, 263–268.Google ScholarPubMed
Schacher, J. F. and Khalil, G. M., 1968.—“Development of Foieyella philistinae Schacher and Khalil, 1967 (Nematoda: Filarioidea) in Culex pipiens molestus with notes on pathology in the arthropod”. J. Parasit., 54, 869–878.CrossRefGoogle Scholar
Spratt, D. M., 1970.—“The synonymy of Agamofilaria tdbanicola and Diro- filaria roemeri”. J. Parasit., 56, 622–623.CrossRefGoogle Scholar
Spratt, D. M., 1972a.—“Aspects of the life-history of Dirofilaria roemeri in naturally and experimentally infected kangaroos, wallaroos and wallabies”. Intl J. Parasit. In press.CrossRefGoogle Scholar
Spratt, D. M., 1972b.—“Natural occurrence, histopathology and developmental stages of Dirofilaria roemeri in the intermediate host”. Intl J. Parasit In press.CrossRefGoogle Scholar
Spratt, D. M. 1972c.—“Histological morphology of adult Dirofilaria roemeri and anatomy of the microfilaria”. Intl J. Parasit In press.CrossRefGoogle Scholar
Williams, H. E., 1955.—“Studies on the bovine Setaria cervi (Rudolphi, 1819)”. Parasitology, 45, 56–62.CrossRefGoogle ScholarPubMed
Wong, M. M., 1964a.—“Studies on microfilaremia in dogs. I. A search for the mechanisms that stabilize the level of microfilaremia”. Am. J. Trop. Med. Hyg., 13, 57–65.CrossRefGoogle Scholar
Wong, M. M., 1964b.—“Studies on microfilaremia in dogs. II. Levels of microfilaremia in relation to immunologic responses of the host”. Am. J. Trop. Med. Hyg., 13, 66–77.CrossRefGoogle ScholarPubMed