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Dementia associated with toxic causes and autoimmune disease

Published online by Cambridge University Press:  08 September 2005

Peter Schofield
Peter Schofield
Affiliation:
Neuropsychiatry Service, Hunter Area Health and University of Newcastle, NSW, Australia
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Abstract

Toxic causes of dementia include exposure to heavy metals such as lead, mercury and aluminum as well as to carbon monoxide and solvents. Autoimmune conditions include such entities as multiple sclerosis, systemic lupus erythematosus, Behçet's disease and Sjögren's syndrome. These conditions share broadly similar cognitive effects giving rise to impairments with subcortical features. Individuals are often affected at a relatively young age. Optimal preventative strategies include avoidance of toxic substances. Comprehensive neuropsychological assessment is valuable not only diagnostically and for monitoring but also to identify the patients' strengths and weaknesses, so that compensatory strategies can be recommended.

Keywords

Dementiacognitive impairmentautoimmuneneurotoxicology
Type
Research Article
Information
International Psychogeriatrics , Volume 17 , Issue s1 , September 2005 , pp. S129 - S147
Copyright
© International Psychogeriatric Association 2005

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