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Assessing Population-Based Programs to Reduce Blood Cholesterol Level and Saturated Fats

Published online by Cambridge University Press:  10 March 2009

Erkki Vartiainen
Affiliation:
National Public Health InstituteFinland
Gregory Heath
Affiliation:
National Public Health InstituteFinland
Earl Ford
Affiliation:
Centers for Disease Control

Abstract

This article reviews seven community-based programs for prevention of cardiovascular disease and their effects on blood cholesterol levels and saturated fat intake. In two programs, cholesterol levels were reduced more in the intervention area than in the reference area. In two other programs, cholesterol increased less in the intervention area than in the reference area. In one program, cholesterol levels initially fell in the intervention group and increased in the reference group; after the first 4 years, the levels also started to increase in the intervention group. The final two programs reduced cholesterol equally in both groups. Only two programs reported on the intake of saturated fats; in both, intake of saturated fat was reduced more in the intervention area than in the reference populations. In one program area, total intake of fat was reduced more than in the reference area. Published data do not allow us to draw conclusions regarding which components of the programs were most important. These studies show that the average blood cholesterol level can be affected in a general population.

Type
Special Section: Assessment Of Preventive Technologies
Copyright
Copyright © Cambridge University Press 1991

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References

1.Abramson, I. H., Gofin, R., Hopp, C., et al. Evaluation of a community program for the control of cardiovascular risk factors: The CHAD program in Jerusalem. Israeli Journal of Medical Science, 1981, 17, 201–12.Google ScholarPubMed
2.Anderson, J. T., Keys, A., & Grande, F.Effects of different food fats on serum cholesterol concentration in man. Journal of Nutrition, 1957, 62, 421–44.CrossRefGoogle ScholarPubMed
3.Blackburn, H.Diet and mass hyperlipidemia: A public health view. In Levy, R., Rifkind, B., Dennis, B., & Ernst, N. (eds.), Nutrition, lipids and coronary heart disease. New York: Raven Press, 1979, 309–47.Google Scholar
4.Blackburn, H.Research and demonstration projects in community cardiovascular disease prevention. Journal of Public Health Policy, 1983, 4, 398421.CrossRefGoogle ScholarPubMed
5.Blackburn, H.Diet and atherosclerosis: Epidemiological evidence and public health implications. Preventive Medicine, 1983, 12, 2102.CrossRefGoogle ScholarPubMed
6.Dayton, S., Pearce, M. L., Hassimoto, S., et al. A controlled clinical trial of a diet high in unsaturated fat in preventing complications of atherosclerosis. Circulation, 1969,40(suppl. II), 169.CrossRefGoogle Scholar
7.De Backer, G., Kornitzer, M., Dramaix, M., et al. The Belgian Heart Disease Prevention Project: 10-year mortality follow-up. European Heart Journal, 1988, 9, 238–42.CrossRefGoogle ScholarPubMed
8.Elder, J. P., McGraw, S. A., Abrams, D. B., et al. Organizational and community approaches to community-wide prevention of heart disease: The first two years of the Pawtucket Heart Health Program. Preventive Medicine, 1986, 15, 107–17.CrossRefGoogle ScholarPubMed
9.Farquhar, J. W., Fortmann, S. P., Maccoby, N., et al. The Stanford Five City Project: Design and methods. American Journal of Epidemiology, 1985, 122, 323–34.CrossRefGoogle ScholarPubMed
10.Feruglio, G. A., Vanuzzo, D., Di Muro, G., et al. The Martignacco project: A community study. Outlines and preliminary results after four years. Giornale di Arteriosclerosis, 1983, 2, 207–17.Google Scholar
11.Feruglio, G. A., Vanuzzo, D., & Pilotto, L. Ten-year results of the Martignacco comprehensive cardiovascular control program. Preliminary results. Abstract no. 354. 2nd International Conference on Preventive Cardiology. Washington, DC: 06 18–22, 1989.Google Scholar
12.Fortman, S. P., Williams, P.T., Hulley, S. B., et al. Effect of health education on dietary behavior: The Stanford Three Community Study. American Journal of Clinical Nutrition 1981, 34, 2030–38.CrossRefGoogle Scholar
13.Frick, M. H., Elo, O., Haapa, K., et al. Helsinki Heart Study: Primary prevention trial with gemfibrosil in middle-aged men with dyslipidemia: Safety of treatment, changes in risk factors and incidence of coronary heart disease. New England Journal of Medicine, 1987, 314, 1237–45.CrossRefGoogle Scholar
14.Grande, F., Anderson, J. T., Chlouverkis, C., et al. Effects of dietary cholesterol on man’s serum lipids. Journal of Nutrition, 1965, 87, 5262.CrossRefGoogle ScholarPubMed
15.German Cardiovascular Prevention Study Research Group. German Cardiovascular Prevention Study. Design, methods, results. Program report 1988. Bonn, Federal Republic of Germany: Scientific Institute of the German Medical Association “WIAD,” 1988.Google Scholar
16.Grande, F., Anderson, J. T., & Keys, A.Serum cholesterol in man and unsaponifiable fraction of corn oil in the diet. Proceedings of the Society for Experimental Biology and Medicine, 1958, 98, 436–40.CrossRefGoogle ScholarPubMed
17.Grande, E, Anderson, J. T., & Keys, A.Comparison of effect of palmitic and stearic acids in the diet on serum cholesterol in man. American Journal of Clinical Nutrition, 1970, 23, 1184–1193.CrossRefGoogle ScholarPubMed
18.Grundy, S. M.Comparison of monounsaturated fatty acids and carbohydrates for lowering plasma cholesterol. New England Journal of Medicine, 1986, 314, 745–58.Google Scholar
19.Gutzwiller, F., Nater, B., & Martin, J.Community-based primary prevention of cardiovascular disease in Switzerland: Methods and results of the National Research Program (NAP 1A). Preventive Medicine, 1985, 14, 482–91.CrossRefGoogle Scholar
20.Heinemann, L., Heine, H., Eckstein, M., & Hellmund, W.Project Schleiz-nationales Demonstrationsproject beholkerungsweiter Pravention bei Herz-Kreislauf- und anderen nichtubertragbaren Krankheiten. Zeitschrift für Klinische Medizin, 1986, 41, 536–69.Google Scholar
21.Hjerman, I., Velve Byre, K., Holme, I., & Leren, P.Effect of diet and smoking intervention on the incidence of coronary heart disease. Report from the Oslo Study Group of a randomized trial in healthy men. Lancet, 1981, ii, 1303–10.CrossRefGoogle Scholar
22.Jacobs, D. R. Jr., Luepker, R. V., Mittelmark, M. B., et al. , Community wide prevention strategies: Evaluation design of The Minnesota Heart Health Program. Journal of Chronic Diseases, 1986, 39, 775–88.CrossRefGoogle ScholarPubMed
23.Keys, A., Anderson, J. T., & Grande, F.Serum cholesterol in man: Diet fat and intrinsic responsiveness. Circulation, 1959, 19, 201–14.CrossRefGoogle ScholarPubMed
24.Keys, A., Anderson, J. T., & Grande, F.Diet type (fats constant) and blood lipids in man. Journal of Nutrition, 1960, 70, 257–66.Google Scholar
25.Keys, A., Anderson, J. T., & Grande, F.Serum cholesterol response to changes in the diet. I. Iodine value of dietary fat versus 2S-P. Metabolism, 1965, 14, 747–58.CrossRefGoogle Scholar
26.Keys, A., Anderson, J. T., & Grande, F.Serum cholesterol response to change in diet. II. Effects of cholesterol in the diet. Metabolism, 1965, 14, 759–65.CrossRefGoogle ScholarPubMed
27.Keys, A., Anderson, J. T., & Grande, F.Serum cholesterol response to changes in diet. III. Differences among individuals. Metabolism, 1965, 14, 766–75.CrossRefGoogle ScholarPubMed
28.Keys, A., Anderson, J. T, & Grande, F.Serum cholesterol response to changes in the diet. IV. Particular saturated fatty acids in the diet. Metabolism, 1965, 14, 776–87.Google Scholar
29.Keys, A., Grande, F., & Anderson, J. T.Fiber and pectin in the diet and serum cholesterol concentration in man. Proceedings of the Society for Experimental Biology and Medicine, 1961, 106, 555–58.CrossRefGoogle ScholarPubMed
30.Kotke, T. E., Puska, P., Salonen, J. T., et al. Projected effects of high-risk versus populationbased strategy in coronary heart disease. American Journal of Epidemiology, 1985, 121, 697704.CrossRefGoogle Scholar
31.Lipid Research Clinics Coronary Primary Prevention Trial. Journal of the American Medical Association, 1984, 251, 365-74.CrossRefGoogle Scholar
32.Miettinen, M., Turpeinen, O., Karvonen, M. K., et al. Effects of cholesterol lowering diet on mortality from coronary heart disease and other causes. A twelve-year clinical trial in men and women. Lancet, 1972, ii, 835-38.CrossRefGoogle Scholar
33.Multiple Risk Factor Intervention Trial. Risk factor changes and mortality results. Journal of the American Medical Association, 1982, 248, 1465-67.CrossRefGoogle Scholar
34.National Institute of Health Consensus Development Conference statement: Lowering blood cholesterol to prevent heart disease. Journal of the American Medical Association, 1985, 253, 2080–86.CrossRefGoogle Scholar
35.Nussel, E., Scheidt, R., Morgenstern, W., et al. Risikofaktoren der koronaren Herzkrankheit- Ansatze zur Korrektur. In Morl, , Dieham, , & Heusel, (eds.), 45. Berlin, Heidelberg, Federal Republic of Germany: Springer-Verlag, 1988.CrossRefGoogle Scholar
36.Pietinen, P., Nissinen, A., Vartiainen, E., et al. Dietary changes in the North Karelia Project (1972–1982). Preventive Medicine, 1988, 17, 183-93.CrossRefGoogle ScholarPubMed
37.Puska, P. (ed.). Comprehensive cardiovascular community control programs in Europe. In EURO Reports and Studies 106. Copenhagen, Denmark: WHO Regional Office for Europe, 1988.Google Scholar
38.Puska, P., Nissinen, A., Tuomilehto, J., et al. The community based strategy to prevent coronary heart disease. Conclusions from the ten years of the North Karelia Project. Annual Review Public Health, 1985, 6, 147-49.Google Scholar
39.Report of International Society Commission for Heart Disease Resources: Optimal resources for primary prevention of atherosclerotic diseases. Circulation, 1984, 70, 157A–205A.Google Scholar
40.The Research Committee to the Medical Research Council. MRC low fat dietary study. Lancet, 1965, ii, 500-04.Google Scholar
41.The Research Committee to Medical Research Council. Soya bean oil trial. Lancet, 1968, ii, 693700.Google Scholar
42.Rinzler, S. H.Primary prevention of coronary heart disease by diet. Bulletin of the New York Academy of Medicine, 1968, 44, 936.Google ScholarPubMed
43.Rose, G.Strategy of prevention: Lessons from cardiovascular disease. British Medical Journal, 1982, 282, 1847-51.CrossRefGoogle Scholar
44.Rose, G., Thomson, W. B., & Williams, R. T.Corn oil in treatment of ischemic heart disease. British Medical Journal, 1965, 1, 1531-33.CrossRefGoogle Scholar
45.Tyroler, H. A.Total serum cholesterol and ischemic heart disease risk in clinical trials and observational studies. American Journal of Prevention Medicine, 1985, 1, 1824.CrossRefGoogle ScholarPubMed
46.UK heart disease prevention project: Incidence and mortality results. Lancet, 1983, i, 1062–65.Google Scholar
47.The World Health Organization European Collaborative Group. European collaborative trial of multifactorial prevention of coronary heart disease: Final report on 6-year results. Lancet, 1986, i, 869–72.Google Scholar