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Transposable element-induced polygenic mutations in Drosophila melanogaster

Published online by Cambridge University Press:  14 April 2009

Trudy F. C. Mackay
Trudy F. C. Mackay
Affiliation:
Department of Genetics, University of Edinburgh, West Mains Road, Edinburgh EH9 3JN
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Summary

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P-element mutagenesis was used to contaminate M-strain second chromosomes with P elements. The effect of P-element transposition on abdominal and sternopleural bristle scores and on female productivity was deduced by comparing the distributions of these quantitative traits among the contaminated second-chromosome lines with a control population of M-strain second-chromosome lines free of P elements. Estimates of P-element-induced mutational variance, Vm, for these characters are very high, and mutational ‘heritabilities’ (Vm/Ve, the ratio of mutational variance to environmental variance) are of the same order as heritabilities of these traits from natural populations. P-element-induced mutational variance of abdominal bristle score is roughly two orders of magnitude greater than spontaneous and X-ray-induced Vm/Ve for this trait.

Type
Research Article
Information
Genetics Research , Volume 49 , Issue 3 , June 1987 , pp. 225 - 233
Copyright
Copyright © Cambridge University Press 1987

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