Hostname: page-component-cd9895bd7-gbm5v Total loading time: 0 Render date: 2024-12-25T15:58:35.648Z Has data issue: false hasContentIssue false
  • English
  • Français

Mapping quantitative trait loci affecting sternopleural bristle number in Drosophila melanogaster using changes of marker allele frequencies in divergently selected lines

Published online by Cambridge University Press:  01 October 1998

SERGEY V. NUZHDIN ,
PETER D. KEIGHTLEY ,
ELENA G. PASYUKOVA  and
ELENA A. MOROZOVA
SERGEY V. NUZHDIN
Affiliation:
Department of Genetics, North Carolina State University, Raleigh, NC 27695, and Section of Evolution and Ecology, University of California at Davis, Davis, CA 95616-5755, USA
PETER D. KEIGHTLEY
Affiliation:
Institute of Cell, Animal and Population Biology, University of Edinburgh, West Mains Road, Edinburgh EG9 3JT, Scotland
ELENA G. PASYUKOVA
Affiliation:
Institute of Molecular Genetics, Kurchatov Square, Moscow 123182, Russia
ELENA A. MOROZOVA
Affiliation:
Institute of Molecular Genetics, Kurchatov Square, Moscow 123182, Russia
Rights & Permissions [Opens in a new window]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Quantitative trait loci (QTLs) responsible for variation in sternopleural bristle number in crosses between the laboratory lines of Drosophila melanogaster OregonR and CantonS were mapped using information from allele frequency changes of two families of retrotransposon markers in divergently selected populations. QTL effects and positions were inferred by likelihood, using transition matrix iteration and Monte Carlo interval mapping. Individuals from the selected populations were genotyped for markers spaced at an average distance 4.4 cM. Four QTLs of moderate effect ranging from 0·6 to 1·32 bristles accounted for most of the selection response. A permutation test of the correspondence between the mapped QTLs and the positions of bristle number candidate genes suggested that alleles at these candidate genes were no more strongly associated with selected changes in marker allele frequency than were randomly chosen positions in the genome.

Type
Research Article
Information
Genetics Research , Volume 72 , Issue 2 , October 1998 , pp. 79 - 91
Copyright
© 1998 Cambridge University Press