Hostname: page-component-7bb8b95d7b-dtkg6 Total loading time: 0 Render date: 2024-09-17T04:08:56.920Z Has data issue: false hasContentIssue false
  • English
  • Français

Interactions between de-repressed F-like R factors and wild type Colicin B factors: superinfection immunity and represser susceptibility

Published online by Cambridge University Press:  14 April 2009

Anna Frydman  and
Elinor Meynell
Anna Frydman
Affiliation:
Department of Microbiology, Lister Institute of Preventive Medicine, Chelsea Bridge Road, London, S. W. 1
Elinor Meynell
Affiliation:
Department of Microbiology, Lister Institute of Preventive Medicine, Chelsea Bridge Road, London, S. W. 1

Extract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

F-like R factors are related to ColB-K77, but not to ColB-K98 or ColB-K166, by the criterion of superinfection immunity. Tests of de-repressed mutant R factors for susceptibility to repression by ColB-K98, known to produce represser for F, showed that these could be either repressor-sensitive or insensitive. The former were independently shown not to produce repressor, which was thus, presumably the reason for their de-repressed state.

Type
Research Article
Information
Genetics Research , Volume 14 , Issue 3 , December 1969 , pp. 315 - 322
Copyright
Copyright © Cambridge University Press 1969

References

REFERENCES

Anderson, E. S. & Lewis, M. J. (1965). Drug resistance and its transfer in Salmonella typhimurium. Nature, Lond. 206, 579–583.CrossRefGoogle ScholarPubMed
Arber, W. & Linn, S. (1969). DNA modification and restriction. A. Rev. Biochem. 38, 467–500.CrossRefGoogle ScholarPubMed
Arber, W. & Morse, M. L. (1965). Host specificity of DNA produced by Escherichia coli. Effects on bacterial conjugation. Genetics, Princeton 51, 137–148.CrossRefGoogle ScholarPubMed
Beckwith, J. (1967). Regulation of the lac operon. Science, N.Y. 156, 597–604.CrossRefGoogle ScholarPubMed
Clowes, R., Hausmann, C., Nisioka, T. & Mitani, M. (1968). Interactions of ColB and R factors and electron microscopy of R factor DNA. Proc. XII Int. Congr. Genet. Tokyo 2, 241.Google Scholar
Dubnau, E. & Maas, W. (1968). Inhibition of replication of an F'lac episome in Hfr cells of Eecherichia coli. J. Bact. 95, 531–539.CrossRefGoogle Scholar
Egawa, R. & Hirota, Y. (1962). Inhibition of fertility by multiple drug resistance factor in Escherichia coli K12. Jap. J. Genet. 37, 66–69.CrossRefGoogle Scholar
Fredericq, P. (1957). Colicins. A. Rev. Microbiol. 11, 7–22.CrossRefGoogle ScholarPubMed
Hausmann, C. & Clowes, R. (1968). Fertility repression by colicinogenic B factors in Escherichia coli. Bact. Proc. p. 54.Google Scholar
Jacob, F. & Monod, J. (1961). Genetic regulatory mechanisms in the synthesis of proteins. J. molec Biol. 3, 318–356.CrossRefGoogle ScholarPubMed
Kahn, P. & Helinski, D. R. (1964). Relationship between colicinogenic factors El and V and an F factor in Escherichia coli. J. Bact. 88, 1573–1579.CrossRefGoogle Scholar
Lawn, A. M., Meynell, E., Meynell, G. G. & Datta, N. (1967). Sex pili and the classification of sex factors in the Enterobacteriaceae. Nature, Lond. 216, 343–346.CrossRefGoogle ScholarPubMed
Lederberg, J., Cavalli, L. L. & Lederberg, E. M. (1952). Sex compatibility in Escherichia coli. Genetics, Princeton 37, 720–730.CrossRefGoogle ScholarPubMed
Maas, R. (1963). Exclusion of an F'lac episome by an Hfr gene. Proc. natn. Acad. Sei. U.S.A. 50, 1051–1055.CrossRefGoogle Scholar
Macfarren, A. C. & Clowes, R. C. (1967). A comparative study of two F-like colicin factors, ColV 2 and ColV 3, in Escherichia coli K12. J. Bact. 94, 365–377.CrossRefGoogle Scholar
Meynell, E. & Cooke, M. (1969). Repressor-minus and operator-constitutive de-repressed mutants of F-like R factors: their effect on chromosomal transfer by HfrC. Genet. Res., Camb. 14, 309–313.CrossRefGoogle ScholarPubMed
Meynell, E. & Datta, N. (1967). Mutant drug resistance factors of high transmissibility. Nature, Lond. 214, 885–887.CrossRefGoogle ScholarPubMed
Meynell, E. & Datta, N. (1969). Sex factor activity of drug-resistance factors. Ciba Foundation Symposium on Bacterial Episomes and Plasmids. Ed. Wolstenholme, G. E. W. and O'Connor, M.. London: J. & A. Churchill Ltd.Google Scholar
Meynell, E., Meynell, G. G. & Datta, N. (1968). Phylogenetic relationships of drug-resistance factors and other transmissible bacterial plasmids. Bact. Rev. 32, 55–83.CrossRefGoogle ScholarPubMed
Meynell, G. G. (1969). Exclusion, superinfection immunity and abortive recombinants in I+ × 1+ bacterial crosses. Genet. Res., Camb. 13, 113–115.CrossRefGoogle ScholarPubMed
Puig, J. & Nagel De Zwaig, R. (1964). Étude génétique d'un facteur colicinogène B et son influence sur la fertilité des croisements chez Escherichia coli K12. Annls Inst. Pasteur, Paris 107 (No. 5 Suppl.), 115–131.Google Scholar
Scaife, J. & Gross, J. D. (1962). Inhibition of multiplication of an F-lac factor in Hfr cells of Escherichia coli K12. Biochem. biophys. Res. Commun. 7, 403–407.CrossRefGoogle Scholar
Schell, J., Glover, S. W., Stacey, K. A., Broda, P. M. A. & Symonds, N. (1963). The restriction of phage T 3 by certain strains of Escherichia coli. Genet. Res., Camb. 4, 483–484.CrossRefGoogle Scholar
Strobel, M. & Nomura, M. (1966). Restriction of the growth of bacteriophage BF 23 by a colicine (ColI-P9) factor. Virology 28, 763–764.CrossRefGoogle Scholar
Watanabe, T. (1963). Infective heredity of multiple drug resistance in bacteria. Boct. Rev. 27, 87–115.Google ScholarPubMed
Watanabe, T., Nishida, H., Ogata, C., Arai, T. S. & Sato, S. (1964). Episome-mediated transfer of drug resistance in Enterobacteriaceae. VII. Two types of naturally occurring R factors. J. Baci. 88, 716–726.CrossRefGoogle ScholarPubMed
Watanabe, T. & Okada, M. (1964). New type of sex factor-specific bacteriophage of Escherichia coli. J. Bact. 87, 727–736.CrossRefGoogle ScholarPubMed
Watanabe, T., Takano, T., Arai, T., Nishida, H. & Sato, S. (1966). Episome-mediated transfer of drug resistance in Enterobacteriaceae. X. Restriction and modification of phages by fi – R factors. J. Bact. 92, 477–486.CrossRefGoogle ScholarPubMed