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Chromosomal location of a mutation causing chloramphenicol resistance in Escherichia coli K 12

Published online by Cambridge University Press:  14 April 2009

E. C. R. Reeve  and
D. R. Suttie
E. C. R. Reeve
Affiliation:
Institute of Animal Genetics, West Mains Road, Edinburgh 9
D. R. Suttie
Affiliation:
Institute of Animal Genetics, West Mains Road, Edinburgh 9
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A chloramphenicol-resistant mutation in Escherichia coli K 12, cmlA1 (previously designated 1a), giving a higher Cm-resistance than other mutations yet examined, has been shown to have a chromosomal location, the gene order being gal, λ, bio, cmlA, pyrD. CmlA can be transduced efficiently into cm-sensitive strains by P1 with little phenotypic lag, and is co-transduced with the λ-attachment site (frequency 1·13%) but not with gal or pyrD.

Type
Research Article
Information
Genetics Research , Volume 11 , Issue 1 , February 1968 , pp. 97 - 104
Copyright
Copyright © Cambridge University Press 1968

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