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A GENERIC FRAMEWORK FOR MAKING CLINICAL DECISIONS INTEGRATING DIAGNOSTIC AND THERAPEUTIC RESEARCH EVIDENCE IN PRETERM BIRTH

Part of: Bespoke shallow archive Weizmann

Published online by Cambridge University Press:  16 October 2003

KS KHAN ,
HONEST  and
LM BACHMANN
KS KHAN
Affiliation:
Department of Obstetrics and Gynaecology, Birmingham Women's Hospital, United Kingdom Khalid S Khan, Department of Obstetrics and Gynaecology, Birmingham Women's Health Care NHS Trust, Birmingham B15 2TG, United Kingdom.
HONEST
Affiliation:
Department of Obstetrics and Gynaecology, Birmingham Women's Hospital, United Kingdom
LM BACHMANN
Affiliation:
Horten Centre, University of Zurich, Switzerland.
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Extract

Ancient Egyptian medical papyri (1550BC) emphasised diagnosis by examination as the cornerstone of the decision to treat or not to treat an ailment. Today the information about the likelihood of diagnosis (and related prognosis) that interventions purport to treat comes from a combination of tests as shown in Figure 1. In addition to easy-to-obtain history (risk factors and symptoms) and examination (signs), current testing includes sophisticated investigations (haematology, biochemistry, radiology, microbiology, etc), which can also be invasive and expensive. Obstetricians routinely incorporate many test results into decision-making concerning management of women at risk of preterm birth, but studies to examine the ways in which even a small number of these tests alter the benefit and harm of treatments are rare.

Type
Research Article
Information
Fetal and Maternal Medicine Review , Volume 14 , Issue 3 , August 2003 , pp. 239 - 249
Copyright
© Cambridge University Press 2003

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