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Phenomenology and neural correlates of formal thought disorder
Published online by Cambridge University Press: 23 March 2020
Abstract
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Speech and language disorders, such as concretism and formal thought disorder (FTD) are core symptoms of Schizophrenia, but do occur to a similar extent in other diagnoses such as bipolar disorder and major depression. We will review clinical rating scales of FTD and introduce a new, validated scale, the TALD. Further, structural and functional brain imaging data will be reviewed and own novel findings presented, relating speech and language dysfunctions to neural networks, within schizophrenia and across the “functional psychoses”. The impact of genetic variance and NNDA receptor blockage on brain function will be addressed with a particular focus on speech and language (dys-) function. We demonstrate, from the genetic to the brain structural and functional level, that particular aspects of the neural language system are disrupted in patients with FTD across traditional diagnoses.
Disclosure of interest
The author has not supplied his declaration of competing interest.
- Type
- S108
- Information
- European Psychiatry , Volume 33 , Issue S1: Abstracts of the 24th European Congress of Psychiatry , March 2016 , pp. S52
- Copyright
- Copyright © European Psychiatric Association 2016
References
Further reading
Kircher, T Krug, A Stratmann, M Ghazi, S Schales, C Frauenheim, M, et al. A rating scale for the assessment of objective and subjective formal Thought and Language Disorder (TALD). Schizophr Res 2014;160(1–3):216–21.CrossRefGoogle ScholarPubMed
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